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oldmantime
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17 Sep 2011, 10:22 pm

John_Browning wrote:
oldmantime wrote:
John_Browning wrote:
An active infection would easily be detected in the person's antibodies. If a virus is sitting in a person's digestive tract without attacking any cells to reproduce, it is not doing anything and is not an issue. Even if it is reproducing, they are still a long way from showing any effect on brain activity much less showing a link to autism.


are you sure this is a typical active infection they are referring to?

No. If it was active, they would show symptoms. If a virus just laying there not doing anything, it does not contribute to symptoms. It eventually gets eliminated with waste products or gets attacked by the immune system and goes away. I'd be really curious to see where their funding is coming from.


there's no way it could be having any other effect? there are no other mechanisms that this virus could possibly engage? i'm not so sure myself. it's too bad the article didn't do much to elaborate.



aghogday
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17 Sep 2011, 11:24 pm

Here is research published yesterday, yes, yesterday for real, that provides evidence that regressive autism is associated with bowel problems, however the research scientists provide evidence other than vaccines as to what may be behind the association.

"Impaired Carbohydrate Digestion and Transport and Mucosal Dysbiosis in the Intestines of Children with Autism and Gastrointestinal Disturbances" (Sept 16, 2011)

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Gastrointestinal disturbances are commonly reported in children with autism, complicate clinical management, and may contribute to behavioral impairment. Reports of deficiencies in disaccharidase enzymatic activity and of beneficial responses to probiotic and dietary therapies led us to survey gene expression and the mucoepithelial microbiota in intestinal biopsies from children with autism and gastrointestinal disease and children with gastrointestinal disease alone. Ileal transcripts encoding disaccharidases and hexose transporters were deficient in children with autism, indicating impairment of the primary pathway for carbohydrate digestion and transport in enterocytes. Deficient expression of these enzymes and transporters was associated with expression of the intestinal transcription factor, CDX2. Metagenomic analysis of intestinal bacteria revealed compositional dysbiosis manifest as decreases in Bacteroidetes, increases in the ratio of Firmicutes to Bacteroidetes, and increases in Betaproteobacteria. Expression levels of disaccharidases and transporters were associated with the abundance of affected bacterial phylotypes. These results indicate a relationship between human intestinal gene expression and bacterial community structure and may provide insights into the pathophysiology of gastrointestinal disturbances in children with autism.



http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0024585



John_Browning
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18 Sep 2011, 1:24 am

The majority of all ASD's involve bowel problems. That's nothing new and that research doesn't explain how (if at all) the gastric issues affect the brain, or if the gastric issues develop first, or if the brain and gastric issues develop at the same time. This research does not explain how autism is caused. Correlation =/=causation.


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jojobean
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18 Sep 2011, 8:50 am

I agree with another poster about how there ws no control group in the study. what about all those kids that were vacinated without autism. If autism was caused by vacines in the way that the author suggested, then 85 percent of the population would have autism...then we would be the majority and thus autism would not be seen as a problem.


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oldmantime
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19 Sep 2011, 1:27 pm

i think the idea is that some people are more vulnerable than others.