This is a problem that many Aspies have, including myself at times. At times they may introvertedly focus so much on their interests/obsessions, and on what they want to talk about, that they forget that the other person may not be interested. I've gotten better in this regard, but sometimes I just can't tell if the person is uninterested (especially if they are being polite and not saying "i don't care").
Here's some basic signs I found:
* The person is trying to change the subject
* Does not give thoughtful responses to what you are saying
* It seems they aren't fully listening to you or paying attention (and likely because they aren't interested)
* They aren't actively approaching you on the subject ; You approach them on the subject always.
* You have to remind them. If someone is really interested, they rarely need to be reminded.
Any other signs?
Your thoughts?