What SSRIs worked/didn't work for you?

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Citalopram did nothing for my depression and may actually have made me worse overall. It certainly had some nasty side-effects for me including but not limited to: lethargy, drowsiness, nausea, sexual dysfunction, laughing or sobbing uncontrollably, increased aggression, dizziness and the infamous electric shocks and "brain zaps". Definitely a drug to use, as they say, at your own risk.

Anti-depressants never worked very well for me. Webutrin, SSRI's or others did very little. My depression seemed to respond better to the situation. If things were "moving forward" and I felt I was making progress, I would be less depressed. When I felt stuck, the depression worsened. The more stuck I felt (feel) the worse the depression.

FWIW, I've been taking Adderal recently for executive functioning. It actually seems to help some. I seem to have less distractibility. It doesn't help any with longer range planning issues typical of EF dysfunction. But it's a start.

The SSRIs all "worked" at first, then they all failed eventually, despite upped dosages.

The tricyclics were awful (they didn't have SSRIs when I was first put on meds) - trazodone blunted my every emotion and mood, and elavil gave me diarrhea so bad I couldn't leave home.

All in all - no more medication for me, though people on here have some good points about it being able to help lift you to a place where you can look at your thoughts more objectively.

Ten years ago I was given a six month dose of Lustral [Sertraline] it turned me manic.

That was the only time I have taken SSRIs under medical supervision.

I trust just St. John's Wort now.

Zoloft worked okay for me. I was on 200 mg/day for 8 months and my depression became a lot less severe for years. It didn't come back until I lost a job.