I don't think it's likely to be a great idea, at least it didn't work well for me. Usually, if you are male, unless you are of a certain age where it is more normal to go the pub alone (middle aged-elderly) or it is a particularly friendly place, you may well be viewed negatively ("odd", "creepy", "loner") if you are drinking alone and this may cause it to be difficult to interact on a friendly level with people. This is likely to be particularly exacerbated if you have some particular aspie traits like struggling with eye contact and reading people. If you are female it is likely you would get a lot of attention as a lone woman in a pub but probably for all the wrong reasons.
On the other hand there have been a couple of occasions when I have met nice people drinking alone but overall I don't find the hit rate of nice people to be worth all the associate stresses. Of course this is all pure anecdote and YMMV.