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AS and know your Neanderthal DNA %?
I have no idea. 63%  63%  [ 15 ]
Yes, it is less than 1%. 4%  4%  [ 1 ]
Yes, it is less than 1.5%. 0%  0%  [ 0 ]
Yes, it is less than 2%. 0%  0%  [ 0 ]
Yes, it is less than 2.25%. 4%  4%  [ 1 ]
Yes, it is less than 2.5%. 0%  0%  [ 0 ]
Yes, it is less than 2.75%. 4%  4%  [ 1 ]
Yes, it is less than 3%. 8%  8%  [ 2 ]
Yes, it is less than 4%. 13%  13%  [ 3 ]
Yes, it is over 4%. 4%  4%  [ 1 ]
Total votes : 24

FireBird
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04 Dec 2014, 1:51 pm

I have 3.2% Neanderthal DNA from 23 and Me. 99% percentile.



naturalplastic
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04 Dec 2014, 4:42 pm

Wow, some high percentiles coming in. Maybe there is something to it.



Janissy
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04 Dec 2014, 6:41 pm

I am 2.7% Neanderthal.

The 23andme forums actually have a number of threads devoted to this topic. rdos (who may be the same rdos who posts here) has a thread where he asks people to both take the rdos quiz and also say what percentage Neanderthal DNA they have. Many people have answered, both NT and AS. He is trying to get as large a sample size as he can. He has. mix of people on and off the spectrum answering.

It's an interesting subject but I am dubious. Hanging the theory on the observation that Neanderthals did less social networking than Homo sapiens sapiens (per obviously traded artifacts) is a stretch. It isn't known why they didn't. That their neurology worked against it is just an assumption. It could have been some other difference.

To really investigate this, autism rates would have to be checked against people who have zero Neanderthal DNA. And it would have to be checked by DNA testing, not just assuming based on geography. The other tough part is how and if testing is done in other parts of the world.



Nonperson
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04 Dec 2014, 6:58 pm

eggheadjr wrote:
ksf777 wrote:
There being no strong evidence of neanderthal DNA coming from Africa yet there are African-Americans people with autism I would tend to believe there is no correlation.


And yet I find the Neanderthal Theory of Autism to be intriguing...


Africans or African-Americans? Because most African-Americans have some European ancestry.



Graelwyn
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04 Dec 2014, 9:50 pm

Hmm, quite expensive to get the kit and testing, but I have bookmarked the site and intend on doing this.
I wonder if it can pick up Irish ancestry ?


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starkid
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05 Dec 2014, 6:36 pm

ksf777 wrote:
There being no strong evidence of neanderthal DNA coming from Africa yet there are African-Americans people with autism I would tend to believe there is no correlation.


Plenty of Americans of African descent also have some amount of European ancestry.

https://en.wikipedia.org/wiki/Quadroon



kraftiekortie
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05 Dec 2014, 6:54 pm

I just don't believe Neanderthals had autistic characteristics. I feel cognitive dissonance at the very concept--not because I believe autism's a negative thing--but because they had to cooperate with each other in order to survive.



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09 Dec 2014, 12:56 pm

I first encountered this idea through RDOS. At first, it seemed repugnant to me. Then I started reading about Neanderthal and wondering about them. We do know some things about them that are fairly certain. That they lived in small groups of 10 to 15 people, occupying the same campsites for many generations. There is no evidence of long distance trade and only a little of short distance trade. Genetic survival requires a group of about 250 reproductive individuals, and they survived for at least 250,000 years, so they must have mixed it up with their neighbors a bit.

The main meat that appears in their diet is reindeer. These are relatively small animals, easier to hunt than mammoths, which I suspect they mostly scavenged for their giant bones, as there is evidence of Neanderthal shelters built of mammoth bones. There is evidence that they made use of trap pits for catching prey, and this would also have made hunting easier in small groups and maybe explains why the women seem also to have been hunters. There is much evidence that they cared for the old and sick. Their survival no doubt depended on compassion to others in the group. In such a small group, everyone counted.

Other evidence seems strong that they had to have made tight fitting clothes. They are probably the inventers of clothing, as it would not have been needed in Tropical Africa. There is also evidence that they must have stored food for winter in order to have survived. They developed a complex procedure for extracting pitch from birch trees for hafting spear tips, so they had the capacity for complex thought and action.

The reason it makes sense to me that it is connected to autism is that to live and survive in Ice Age Europe for so long, they must have had to be very adapted to long periods inside a shelter waiting for spring and hunting season. It would have been a perfect selection environment for quiet, inward, self-occupied people with low social needs. It seems to me that flexible sexuality and a tendency to asexuality would also be adaptive: Having a baby in the wrong season in Ice Age Europe may well have been fatal for mother and child.

Their DNA appears to be wide spread in non-Sub Saharan African people, so clearly there was interbreeding and some adaptive advantage to Neanderthal genes. Considering that many autistics are very clever at problem solving that involves huge amounts of solitary thought and experiment, as well as having very low social needs, it seems like Neanderthal genetics could have something to do with it. RDOS's examination of the evidence seems to support the hypothesis as well as results here so far.



eric76
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09 Dec 2014, 1:57 pm

emtyeye wrote:
Personally, I suspect that Neanderthal DNA is a contributing factor to AS neurology. But, I am looking forward to all opinions and information on the subject.


Is there any actual reason for suspecting that?

I know that there are people who almost seem desperate about "proving" a link, but there is no evidence at all to suggest a link actually exists. As I understand it, we all contain some amount of Neanderthal DNA, at least those with some level of European ancestry. If Neanderthal DNA was responsible for Aspergers, then Aspergers would likely be far more common than it is.

I'm surprised nobody has come up with the claim that Asperger's is due to viral DNA. I guess that people would rather say they were more Neanderthal-like than virus-like.



eric76
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09 Dec 2014, 2:00 pm

slenkar wrote:
I've read the theories over at
http://rdos.net/eng/asperger.htm

I found it to be pretty convincing.

There is no one 'slam dunk' fact, it is a bunch of little facts all piled up to prove the theory.


I wouldn't call it a bunch of little facts. Maybe a bunch of wild conjectures packaged as "facts".