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Do you want to know what gene(s) caused your autism?

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HeroOfHyrule
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13 Oct 2021, 1:53 pm

I personally always wonder what specific gene(s) I have that caused me to develop autism + some of the comorbids I have. Both of my parents have autism/many autistic traits, so I am also interested in if I ended up with one parents ASD-linked gene or both, since I have traits both of them have + comorbids one or the other doesn't have.

I just would find it super interesting to know these things, and I don't even want to know them for any reason (like concerns for my offspring or something) other than pure curiosity.



GadgetGuru
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13 Oct 2021, 1:56 pm

More data is always welcome.


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funeralxempire
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13 Oct 2021, 2:02 pm

And really small fists so I can punch it. :evil:


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HeroOfHyrule
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13 Oct 2021, 2:04 pm

funeralxempire wrote:
And really small fists so I can punch it. :evil:

But, what if punching it damages it and gives you extra autism? 8O



HeroOfHyrule
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13 Oct 2021, 2:05 pm

GadgetGuru wrote:
More data is always welcome.

I like that way of looking at it! lol

I definitely would love to have more "data" on myself.



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13 Oct 2021, 2:15 pm

HeroOfHyrule wrote:
funeralxempire wrote:
And really small fists so I can punch it. :evil:

But, what if punching it damages it and gives you extra autism? 8O


I thought that was just vaccines and a lack of Jesus. :|
At least that's what Terri-Lynn told me one day. I haven't always had the brightest coworkers.


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carlos55
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13 Oct 2021, 2:18 pm

HeroOfHyrule wrote:
I personally always wonder what specific gene(s) I have that caused me to develop autism + some of the comorbids I have. Both of my parents have autism/many autistic traits, so I am also interested in if I ended up with one parents ASD-linked gene or both, since I have traits both of them have + comorbids one or the other doesn't have.

I just would find it super interesting to know these things, and I don't even want to know them for any reason (like concerns for my offspring or something) other than pure curiosity.


From your profile, you may live in the US, you could contact SPARK who would test your genes & maybe your parents for free & give you feedback.

https://sparkforautism.org/registration ... ack-button

If you are willing to pay there is also some dr`s although its quite expensive maybe $2-3k or more, that specialises in analysing for autistic genes in patents for a fee & giving feedback on their findings.


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HeroOfHyrule
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13 Oct 2021, 2:25 pm

carlos55 wrote:
HeroOfHyrule wrote:
I personally always wonder what specific gene(s) I have that caused me to develop autism + some of the comorbids I have. Both of my parents have autism/many autistic traits, so I am also interested in if I ended up with one parents ASD-linked gene or both, since I have traits both of them have + comorbids one or the other doesn't have.

I just would find it super interesting to know these things, and I don't even want to know them for any reason (like concerns for my offspring or something) other than pure curiosity.


From your profile, you may live in the US, you could contact SPARK who would test your genes & maybe your parents for free & give you feedback.

https://sparkforautism.org/registration ... ack-button

If you are willing to pay there is also some dr`s although its quite expensive maybe $2-3k or more, that specialises in analysing for autistic genes in patents for a fee & giving feedback on their findings.

Oh, thank you! I'll look into that.



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13 Oct 2021, 2:30 pm

funeralxempire wrote:
I thought that was just vaccines and a lack of Jesus. :|


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13 Oct 2021, 2:37 pm

Science is working on it ...if haphazardly. Its not the Apollo Program. But theyre working on it.

They probably arent going find one specific gene, on one specific chromosome, that is the one and only cause of autism.

But they already found that certain variants of certain genes "correlate to autism". Posts have been about it here. Different types of autism are going to be found to correlate to different kinds of genetic and epigenetic causes.

=======

Or maybe it IS vaccines. Or...those hideous post WWII CIA experiments with creating human-porpoise hybrids!



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13 Oct 2021, 2:38 pm

Note: SPARK does not commit to giving you a personal genetic report. From their website FAQ:

Quote:
Will everybody in SPARK receive genetic results?

No. Because SPARK is a research study, our genetic analysis is not like a clinical genetic test or commercial sequencing service. SPARK provides genetic results in the form of a clinical report only if we discover a genetic change associated with autism.
Not everyone in SPARK will have genetic findings linked to autism. Based on what we know today about genes that are linked to autism, SPARK scientists expect to find a genetic difference linked to autism in 5% to 10% of people in the study. This number will increase as we learn more about autism and identify more genes that are linked to autism.
There is also a chance that we will find genes linked to autism in your sample only after we have studied genes from many other families and compared them with yours. In this case, it could be years before there are results to return. Keep in mind that genes are not the only cause of autism, so not all people with autism will have a genetic difference.
I gave them my DNA sample in August 2020. No news for me.

The website lists "over 200 genes and segments of chromosomes, known as copy number variants (CNVs), that are related to autism." But, that's not that to get Autism you need all of those genetic changes but rather any one of them. Or not. I think this means the Autism Spectrum might be very complicated.

Personally, I don't see how Science can properly study Autism until it can distinguish those 200+ varieties of it to see what characterizes each.


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HeroOfHyrule
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13 Oct 2021, 2:45 pm

Double Retired wrote:
Note: SPARK does not commit to giving you a personal genetic report. From their website FAQ:
Quote:
Will everybody in SPARK receive genetic results?

No. Because SPARK is a research study, our genetic analysis is not like a clinical genetic test or commercial sequencing service. SPARK provides genetic results in the form of a clinical report only if we discover a genetic change associated with autism.
Not everyone in SPARK will have genetic findings linked to autism. Based on what we know today about genes that are linked to autism, SPARK scientists expect to find a genetic difference linked to autism in 5% to 10% of people in the study. This number will increase as we learn more about autism and identify more genes that are linked to autism.
There is also a chance that we will find genes linked to autism in your sample only after we have studied genes from many other families and compared them with yours. In this case, it could be years before there are results to return. Keep in mind that genes are not the only cause of autism, so not all people with autism will have a genetic difference.
I gave them my DNA sample in August 2020. No news for me.

The website lists "over 200 genes and segments of chromosomes, known as copy number variants (CNVs), that are related to autism." But, that's not that to get Autism you need all of those genetic changes but rather any one of them. Or not. I think this means the Autism Spectrum might be very complicated.

Personally, I don't see how Science can properly study Autism until it can distinguish those 200+ varieties of it to see what characterizes each.

Oh, thank you! That's a bummer that they don't do that. :/

Also, I think that's why I'd like to know what gene(s) caused my autism, because it'd be interesting to just know what the genes do, and also to look out for more information about them and their role in ASD + the characteristics people figure out that "type" of autism has.



kraftiekortie
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13 Oct 2021, 3:20 pm

I would venture to guess that it's more likely there are "many autisms," rather than "one autism."



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13 Oct 2021, 4:01 pm

I'm also curious where it came from and what kind it actually is.

Because inheritance doesn't look like it in my case. I'm not one of those people who have many ND relatives.
Maybe it is a mutation :lol: or not.

Nor did known pre-natal causes.
Nor did known while birthing causes.

Nor did known outsides causes.
Vaccines? I was shot too late. I may not have it as many as the US standard gets.
Trauma? I wish. There's no one else around my own age group even and many had it worse.


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13 Oct 2021, 5:10 pm

Well both my parents are neurotypical, but have managed to produce 2 emotionally insecure Aspies. My half-sister is 100% neurotypical so I don't think the autism has come from my dad's side, it must have come from my mum's side. My mum has a sister with (undiagnosed) autism but her child is neurotypical.

In all fairness, me and my brother should both be neurotypicals and my aunt's child should be autistic. But no, it can't work like that can it. It has to be ME cursed with this f*****g s**t.


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13 Oct 2021, 5:17 pm

Edna3362 wrote:
I'm also curious where it came from and what kind it actually is.

Because inheritance doesn't look like it in my case. I'm not one of those people who have many ND relatives.
Maybe it is a mutation :lol: or not.

Nor did known pre-natal causes.
Nor did known while birthing causes.

Nor did known outsides causes.
Vaccines? I was shot too late. I may not have it as many as the US standard gets.
Trauma? I wish. There's no one else around my own age group even and many had it worse.

I'm curious about where it came from in my case, too. I know it's familial and my parents + some of their relatives have it/have traits, but I wanna know which ancestor(s) had it first and how long those gene(s) have been in my family.