New Department of Defence Study Uses Antibiotic For Autism

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JohnT
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12 Apr 2011, 8:40 pm

A currently ongoing study seeks participants with the autistic spectrum and uses Seromycin, an antibiotic to this point used almost exclusively for tuberculosis.

The study being run by the University of Indiana and the Department of Defense.



pensieve
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12 Apr 2011, 8:47 pm

What symptoms does it treat?


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ooOoOoOAnaOoOoOoo
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12 Apr 2011, 8:51 pm

How strange the study would be run partially by the Department of Defense...



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12 Apr 2011, 8:56 pm

they must be worried about our growing military capabilities



JohnT
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12 Apr 2011, 9:07 pm

pensieve wrote:
What symptoms does it treat?


The drug Seromycin, as mentioned - an antibiotic for TB, was previously used in animal studies in which it was concluded that it increased the sociability of mice. This previous study mentions that its positive results should hold benefit for kids with autism. So the current DOD study is an offshoot.



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12 Apr 2011, 9:08 pm

Is it a good idea, using an antibiotic for something besides treating a bacterial infection? You don't want more of those super bugs popping up.



JohnT
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12 Apr 2011, 9:17 pm

ooOoOoOAnaOoOoOoo wrote:
Is it a good idea, using an antibiotic for something besides treating a bacterial infection? You don't want more of those super bugs popping up.


This is a commonly used argument by certain practicioners, but not necessarily true. Everything in medicine must be weighed on a scale of benefits versus complications. And it is true that all antibiotics can cause superinfection. Does that mean we should stop using antibiotics? Not at all.

First in importance is whether the condition being treated is caused by a germ that is susceptible to a particular antibiotic. If it is, then delaying to treat it will just let the particular bacteria do more damage to the system, which in the case of autism, is obviously the nervous system.



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12 Apr 2011, 9:20 pm

The antibiotic doesn't cause the super-infection, but it can render certain bacteria more resistant to antibiotics when being treated. How do you know this wouldn't do the same thing? It's happened before, with other antibiotics. What if a super strain of TB develops because of this, people catch it, and it's even harder to treat than regular TB?



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12 Apr 2011, 9:29 pm

Ritalin makes me more social but I'm still not relating to people.

Maybe if I actually tried to work on my social skills...


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JohnT
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12 Apr 2011, 9:34 pm

ooOoOoOAnaOoOoOoo wrote:
The antibiotic doesn't cause the super-infection, but it can render certain bacteria more resistant to antibiotics when being treated. How do you know this wouldn't do the same thing? It's happened before, with other antibiotics. What if a super strain of TB develops because of this, people catch it, and it's even harder to treat than regular TB?



The same could be said of a superstrain of strep or staph (MRSA) or any other pathogen. That dosen't mean you don't treat these.

TB by its very nature is resistant, and is never treated by just one drug. There is widespread drug resistant strains in the world today. On the other hand it kills about 2 milliion plus people a year. If I had it, and the doctor was trying to sell me on this resistance stuff, I would not walk out of his office, I would run.



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12 Apr 2011, 9:40 pm

If you used it to treat TB, it would be using it to treat a bacterial infection which is what it is for which is the point. When used correctly, it kills the bacteria so it doesn't have a chance to become resistant.
If you use it to treat autism, you are no longer using it to kill bacteria. You don't see any conflict there?



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12 Apr 2011, 9:54 pm

I believe it is each person's right to choose to do this if he or she wants to. But as for me, no thanks.


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JohnT
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12 Apr 2011, 10:04 pm

No antibiotic has ever been invented which "kills" TB.

And there is no greater testimony to its resistance than that it most cases an active infection is treated, by a cocktail of at least 3 anti-tubercular drugs.

You are assuming that there is absolutely no relationship between this disease and autism? But it is my belief that results from the current DOD study might well point in exactly this direction.

There is historic precedent here. The first documentation of the entire autistic spectrum was clearly spelled out in a subset of John Langdon Down's children. It was Down who came up with the term "developmentally disabled." And what disease did Down feel, "for the most part" was responsible for his children's symptoms, including those with autism? TB.



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12 Apr 2011, 10:32 pm

JohnT wrote:
A currently ongoing study seeks participants with the autistic spectrum and uses Seromycin, an antibiotic to this point used almost exclusively for tuberculosis.

The study being run by the University of Indiana and the Department of Defense.

When the department of defense does medical experiments, BE AFRAID! BE VERY AFRAID!! ! 8O


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JohnT
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12 Apr 2011, 10:41 pm

Don't understand why, of all the anti-tubercular drugs available, they chose Seromycin. I guess it was because that was the agent used in the earlier autistic animal studies in Virginia. Seromycin itself causes mind-bending changes and isn't the best choice. But that is the antibiotic where the focus is now on. Perhaps they will get it right in future studies.



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12 Apr 2011, 11:04 pm

JohnT wrote:
No antibiotic has ever been invented which "kills" TB.

And there is no greater testimony to its resistance than that it most cases an active infection is treated, by a cocktail of at least 3 anti-tubercular drugs.

You are assuming that there is absolutely no relationship between this disease and autism? But it is my belief that results from the current DOD study might well point in exactly this direction.

There is historic precedent here. The first documentation of the entire autistic spectrum was clearly spelled out in a subset of John Langdon Down's children. It was Down who came up with the term "developmentally disabled." And what disease did Down feel, "for the most part" was responsible for his children's symptoms, including those with autism? TB.

Not sure about that because TB hasn't been widespread in quite a while. Besides, mumps causes a high enough fever that could result in brain damage, which could lead to a developmental disability. How can you blame mumps fever brain damage on TB?