Dude... seriously? Giving up is never an option. I'm in the same boat as you, albeit 9 years younger, and I absolutely won't pretend to be any kind of expert on women... but one thing I have noticed is that even guys that have absolutely nothing going for them can get dates if they are confident in themselves. I know, I know, it's the hardest damn thing in the world to believe in yourself, I have my troubles with it too, every single day. But, I've noticed that a negative attitude is the biggest turn-off ever. And a positive one the biggest turn-on.
I have a good friend, and I'll just say that he is an incredibly strange guy. He's kind of weird-looking too. Yet, he rarely finds himself lonely, bored, frustrated, or any of the things we experience every day. The reason for this, as he'll tell you, and as I believe, is that this guy is consistently happy. Even if he's having the worst day ever by normal people's standards, this guy finds something to be happy about. Lately, I've been trying to go by his outlook on life, and I have actually seen some good results. It's been difficult, and I've for sure slipped back into the pessimistic way of thinking occasionally, especially with some things that have gone on in my life in the past week or so. But trust me, even if you don't see any results romantically, it will at least make you feel a LOT better.