I suppose difficulties interacting with other humans applies across the board to all humans, including others with the same handicaps.
There's a guy on my regular email contacts that I used to work with, who's every bit as textbook Aspie as I am, and a really great person, but we would never be buddies and hang out because our personal interests are different as night and day. Other than working in the same industry for years, we have absolutely nothing in common and would run out of things to talk about in about a half hour, or worse, bore each other to death lecturing on topics the other couldn't care less about.