I think it is. I think I often appear angry or at least uncomfortable in my facial expression. I squint and furrow my brow unconsciously, partly because the light is hurting my eyes.
In terms of reading others expressions I think a lot of it is because I'm not looking at their face. I can usually read facial expressions when I'm shown photos but frequently misread people in real life.
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"No way, you forgot what a bird sounds like? No wonder you're depressed." - Jake the Dog