Autism-Chronic Fatigue Syndrome connection

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I have had chronic fatigue / candida overgrowth. My daughter has had chronic fatigue. Recently my dad was sick and a blood test showed up candida overgrowth in his blood stream.
My son has a diagnosis of aspergers. I have traits but no diagnosis. My dad fits the diagnosis - but he is too old to worry about a getting an offical diagnosis.

I really doubt that it has much to do with mercury.

Antifungals didn't help me - I was allergic due to just about everything. The only thing that helped me was a rotation diet low in simple carbs and sugar.

Candida overgrowth makes you physically sick, over tired and it can cause allergies. It creates symptoms of chronic fatigue. It can cause indigestion and cause allergies to develop as it overgrows and breaks down the mucusal lining of the digestive system.


http://www.creativewellnesscenter.com/candida.html

Actually, there are tests to determine candida infections. At least some of them.

I had a biopsy done of white stuff in my esophagus that turned out to be candida. They can do the same thing for crotch infections of various sorts. And mouth infections. And skin infections. (Of course those, like most candida infections, are localized. And those are the sort I've had recently. Because of prednisone+antibiotics.)

Here are some of the other features that have been reported in the past to be found in autism, which are also found in CFS:

* Oxidative stress
* Toxicity and sensitivity to toxins, especially mercury
* Gastrointestinal problems, including dysbiosis, leaky gut, and problems with casein and gluten.
* Coagulation problems
* Sleep disorders
* HPA axis dysfunction
* Abnormalities in sulfur metabolism

I think Diflucan and Nystatin are the only prescription anti-fungals that work for Candida and some yeast are resistant to Nystatin.

I wrote this in response to another post asking about an ASD-FM connection (CFS is similar)
WARNING - ANTI-CURE & CLOSE-MINDED PEOPLE MAY BE OFFENDED. READ AT YOUR OWN RISK.

First of all, congratulations on the header/disclaimer. Hopefully the discussion will be about the issue rather than silly arguments.

Well, if he really wanted a discussion he would have chosen another heading

Do you know what they mean by "coagulation problems''?
Does it mean your blood takes too long to clot? I have that problem with my blood and I cannot take anything that causes it to get more runny like aspirin or even garlic supplements and vitamin E too.

Pentoxifylline was given to a child with autism in Japan to treat suspected brain damage from an accident. After this treatment, the boy showed marked improvement of his autistic symptoms. When 23 children with autism were treated with pentoxifylline (150-600 mg/day), the drug was reported to be remarkably effective in 10 of the children with some of the group no longer considered to be autistic. The drug was also very effective in treating seizures.

http://www.greatplainslaboratory.com/book/bk7sect2.html

Autism Spectrum Disorders and the Occurrences of Familial Thrombophilia Disorders

An Early Report © Presented at the September 2000 DAN! Meeting, San Diego, California J.J. Bradstreet*, J.J. Katrzinel*, D. Berg, Jt. El-Dahr# *The International Child Development Resource Center, Palm Bay, Florida, 321-953-0278 tHemex Loaboratories, Pheonix, Arizona , #Tulane University Medical Center

Recently, growing evidence points to dysregulation of the immune system in Autism Spectrum Disorders (ASD). Various vaccines, viruses, pathogens, immune deficiencies, toxins and autoantibodies have been put forward as playing a role in the development of autism related symptoms. Additionally, a familial or genetic tendency has been observed in this condition... Because thrombophilia disorders are also associated with immunological disorders, inflammatory bowel diseases, chronic fatigue/fibromyalgia, and central nervous system conditions including multiple sclerosis and cerebral palsy, it is reasonable to investigate a potential for thrombophilia in ASD. To determine this, nine families representing 10 children with ASD and 16 additional family members (15 parents and 1 sibling), selected at random from an ASD population were tested for coagulation disturbances. An Immune System Activation of Coagulation panel (ISAC) consisting of four tests including: Fibrinogen, Soluble Fibrin Monomer, Thrombin/AntiThrombin Complexes, and Platelet Activation by flow cytometry were measured on all children and available family members. In the children with ASD seven of 10 were positive for at least one marker of thrombophilia (ISAC), while 15 of 16 family members were positive for ISAC. The families were further studied by an Hereditary Thrombosis Risk Panel (HTRP) consisting of AntiThrombin Activity, Protein C level, Protein S level, APC Resistance, Factor II Activity, Lp(a) levels, PAI-1 Activity and Homocysteine levels. In the children with ASD, six of 10 had abnormal findings in the HTRP and 11 of 16 family members showed abnormal activated coagulation factors. By combining ISAC with HTRP, 10 of 10 children with ASD were at risk for thrombophilia disorders and 15 of 16 family members were as well. Eleven of the family members reported symptoms consistent with CFS/Fibromyalgia. This represents a previously unreported high prevalence of familial thrombophilia where at least one member has ASD. The data provide further evidence of immune activation in ASD, which deserves additional study to determine the potential pathophysiological role of thrombophilia in the generation of autism related symptoms. Simultaneously, family members deserve careful evaluation for their own thrombophilia-associated conditions.

It has now been scientifically proven that stealth viruses do, indeed, exist and can be at the root of many multi-system neuro-degenrative illnesses, such as chronic fatigue syndrome, fibromyalgia, attention deficit disorder, autism and other diseases causing behavorial changes.

http://www.ccid.org/

Q. A representative of the Great Plains Laboratory asked Dr. De Meirleir to comment on the
fact that they are seeing some similar markers in autism and CFS, FM and multiple sclerosis.

Dr. De Meirleir – Mothers with CFS have 3-4 times perhaps even 10 times more chance of having autistic children. He’s collecting data on this now.

Dr. Hanna closed the session by imploring CFS researchers to be creative in looking for funding
right now. She noted that there’s a lot of money going into autism research right now and
creative CFS researchers could tap into it.

Hmm, I have doxycycline that I don't really take too often anymore.

Also, I forgot to mention in my previous post, as for susceptibility infections: I have an infected toe. I don't know what it is, except that it's bacterial. It has been infected for more than two years. Antibiotics helped but never quite got rid of it. A year later, a pediatrist trimmed the edge of the nail - he didn't do anything to kill the matrix as is usually done with ingrown nails - and told me that taking the pressure off should take care of it. It was almost completely gone within a month, but never went away entirely. In the end, I've given up fighting with it. I can still walk without any problems, and it doesn't hurt at all. It's just perpetually swollen, but only a little.

I don't know if this is related. I just thought it was weird that I would have such a hard time with what seems to be a simple bacterial infection. As far as I know, I got it after I walked into a door (my toe wedged underneath it - ouch) because I was in one of my hazy periods when I ache too much to do hardly anything, all I want to do is sleep and I can't focus on anything. I noticed the infection early and cleaned it up the best I could. But then I went to sleep, assuring myself I would do something about it as soon as I got home.

(I take it "closed-minded" just means "doesn't agree with you"?)

At any rate, I do think there might be a connection, but not necessarily what people think. Autoimmune diseases in general are more common in certain segments of the population. Women, for instance, have a far higher rate, without femaleness being caused by one. Anyone who is under a great deal of stress also experiences more of them. Autistic people tend to be really stressed out. Therefore...