It does have one of the few moments in video gaming that I found actually touching.
Create a character with the background "Sole Survivor". He/she will have been the only human survivor of a batarian raid on the colony world Mindoir.
The second time you go to the Citadel, you will be asked to intervene on behalf of one of the port officers. A young woman was recently rescued by Alliance Marines from a batarian slave camp, and is freaking out all over the docking bay (near the Normandy, as it happens). They want to defuse the situation by giving her a sedative, so she can be treated for her various mental disorder resulting from years of mistreatment at the slavers' hands. As the sole survivor of Mindoir, you are asked to talk her down. Try to choose the gentlest conversational options, so that you can get to the point where you can offer to let her take the sedative herself. During the conversation, she refers to herself in the third person ("because if they can't see her, then it all happened to someone else"), uses vocabulary appropriate to a child, and describes the attack as best she can ("The masters come with hoses and fire. Daddy's coming apart - he's melting! Don't make her see it any more!").
If you manage it, when you offer the sedative, she asks, "Will she have bad dreams?"
I replied, "Only good dreams."
She smiled and said, "She'd like that," then injected herself with the sedative.
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Sodium is a metal that reacts explosively when exposed to water. Chlorine is a gas that'll kill you dead in moments. Together they make my fries taste good.