If you have an RT2x00 wireless USB device, prepare to see it break like mine did
if it didn't already break in 9.10 (now that was a horrible release).
I also hate the inconsistent notification/indicator applet thing, inconsistent because of the spacing and icon styles for programs like banshee, deluge, dropbox, glipper. The new (and sluggish) Ubuntu Software Store is missing icons after an upgrade, my favourite CHM viewer from the repository won't even install without some manual fidgeting about, installation seems to take longer then it did before and nautilus is still ugly as sin (even if it is awesome).
On the plus side, it's pretty easy to swap icon alignment back to the right (where it belongs until they make use of that empty space), it's a stable release, I love the nouveau drivers, Firefox is quickly closing the gap on it's window's version and it's still the snappiest easy to use distro of the lot.
It scores a B from me.