Adding americium to MOX will not make it harder to use the Pu for making a bomb, the Pu can still be recovered from the unused MOX using a simple version of a PUREX process. I am sure that a PUREX process on unused MOX fuel would work as a method of getting the Pu back out of the MOX.
I think the idea of adding Np-237 to spoil Pu is a non starter, it will not prevent anyone getting the Pu-239 out of unused MOX. But it will make the Pu in the used MOX very bad for bomb making, the addition of Np-237 will cause a lot of extra Pu-238 to form in the fuel. Pu-238 has a half life of 80 to 90 years and a little Pu-238 will increase the alpha activity of the Pu a lot and will make it harder to build a bomb. Pu-238 is a nasty isotope to work with on the gram scale, it brings with it contamination issues which are almost as bad as those of radium-226 / radon-222.
A better thing to do if you want to spoil Pu, is to mix bomb grade Pu with Pu from used UOX (or even used MOX) to create Pu with an isotope signature which is mid way between the bomb grade and the Pu from a power reactor after a long irradiation time. This would increase the Pu-240 content of the Pu. After a few uses / recycles of MOX it will have such a bad Pu isotope signature that it is impossible to use it in a thermal reactor such as a PWR or BWR, at that stage the only use will be as fast reactor fuel.
If you want to make pure Pu-239 then it is important to only leave the fuel in the reactor a short time, if you are trying to run the reactor to make cheap electric power then you want to get as much energy out of each fuel rod. So you want to go for a high burn up and a long irradiation time, during this time some of the Pu-239 is converted into Pu-240 and Pu-241.
The Pu-240 is a long lived isotope of Pu which makes it hard to make a Pu based bomb, the Pu-240 undergoes spontaneous fission which forces the bomb builder to have to devise a bomb which goes very quickly from subcritical to supercritical. The Pu-241 is quite short-lived so if you sit back and wait for 30 years then most of the Pu-241 will have vanished
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Health is a state of physical, mental and social wellbeing and not merely the absence of disease or infirmity

I am not a jigsaw, I am a free man !
Diagnosed under the DSM5 rules with autism spectrum disorder, under DSM4 psychologist said would have been AS (299.80) but I suspect that I am somewhere between 299.80 and 299.00 (Autism) under DSM4.