One True Friendships That You've Noticed

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Instead of "One True Pairings", there are some fans who make fan art and fanfics where fictional characters develop platonic feelings for each other. Here are some popular OTFs that I've seen:

Sonic the Hedgehog & MLP:FiM
- Amy Rose & Pinkie Pie
- Bunnie Rabbot & Apple Jack
- Blaze the Cat & Twilight Sparkle
- Sally Acorn & Twilight Sparkle
- Cream the Rabbit & Fluttershy

Super Smash Bros.
- Mario, Sonic, Megaman, Pac-Man
- Marth, Roy, Link, Pit, Ike
- Samus, Peach, Zelda
- R.O.B. and Game & Watch

Misc.
- Rise of the Brave Tangled Dragons, aka the Big Four (Jack Frost, Merida, Rapunzel, Hiccup)
- The Secret Trio (Danny Phantom, American Dragon: Jake Long, Randy Cunningham: 9th Grade Ninja)
- Tigger (Winnie the Pooh) & Pinkie Pie (MLP:FiM)
- Wally "Kid Flash" West (Young Justice) & Aya (Green Lantern: The Animated Series)