Well, none are genres I like for their own sake or as a 'fan', but nor do I dislike them on principle. That is, none would be a reason for me to try something out but, 'space opera' aside, none would put me off.
I mean, I'd probably think of myself who is indifferent to sci fi or cartoons, yet one of my favourite series ever is Futurama, a sci fi cartoon.
Something being an animation does not in any way mean I won't consider it or enjoy it, but nor would I call myself a 'fan' of cartoons. Simpsons up to season 10, Futurama, and my daughters have got me into Gravity Falls - all great. I've tried anime, but it just doesn't work for me.
Same goes for sci fi or fantasy. I'm not really into 'hardware' or alien worlds/space travel. Fantasy I have a bit more inclination towards (it has more aesthetic appeal), but there has been a phenomenal amount of dreck produced in both genres (as in all genres).
I like the weird and uncanny - a good ghost or monster story. And I like things - fiction and fact - that are psychologically interesting/perceptive.
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Of course, it's probably quite a bit more complicated than that.
You know sometimes, between the dames and the horses, I don't even know why I put my hat on.