I am so grateful that our family has turned out the way it has. My son is the oldest of our 5 kids.(by three whole minutes!) He has a very NT and brilliant twin brother who is one of the most mature and empathetic kids you could imagine. This child rarely gets frustrated with his AS twin. He is extremely tolerant of his brother. Since he is so mature, he has rarely annoyed his brother. Last year he did say that is gets embarrassed by his brother sometimes because some of the kids were making comments about his brother. We practiced what he should say to those kids and he has gotten them to stop, at least within his earshot. As far as support in school, I have always separated my boys in class. However, his twin has been extremely helpful in reminding his brother about when stuff is due, etc.
However, his younger sibs push his buttons easily. He has 2 sisters and another brother only 2 1/2 years younger than him (they are triplets). They can be loud and very rambunctious, so they have often gotten on his nerves. It was very difficult for several years feeling as though I lived in a social skills experiment with him and them at home; however, not that the younger ones are turning 8 1/2, and maturing, they get along most of the time now. My AS son is very outgoing. He joins lots of things and is never one to not be noticed. I truly think his siblings have been a positive force in his life.