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jimmy m
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19 Jun 2020, 7:57 am

MORE SIGNS THAT THINGS ARE OPENING BACK UP

One of the stores that opened up this week was BEST BUY. So I had to pay them a visit. One of the things that surprised me was how bare the isles were in the DVDs and Game. It is almost like a trend. I had asked a salesman about the lack of DVDs and he said everyone is switching to streaming content, so people are no longer buying videos on DVDs.

One thing that is mysteriously missing in stores now is the cakes they use for strawberry shortcakes. Strawberries are in season but no cakes to make strawberry shortcakes. What a strange thing to disappear from stores.

I received an email yesterday from AMC Movie Theaters that said the movie theaters will be opening in the middle of July.

ULine suppliers pushed back the restock date for N95 mask from July to August. I have been wearing the same N95 mask for four months now when I am up and about. But it is getting ratty. It needs to be replaced. One mask can provide a long life if you sterilize it after each use using a UVC sterilization box.

I talked to a heating/cooling provider the other day and indeed freezers disappeared at the beginning of the pandemic because many people bought them all up and stocked them with meats and foods like pizza. Thus producing a shortage in grocery stores. There is also a shortage of UVC sanitizers for the ductwork in HVAC units. So the word must have gone out that this is a real solution to the coronavirus pandemic. He said this technology has been out for years but no one spent the little bit of money to buy and install them. Now that the pandemic has hit, there is a run on these little units.


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20 Jun 2020, 5:15 am

WHO Says Coronavirus is ‘Accelerating’ as CDC Predicts Up to 145,000 U.S. Deaths by July 11

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The World Health Organization on Friday said the previous day saw the most new cases reported to the group in a single day so far.

"The pandemic is accelerating," WHO Director General Tedros Adhanom Ghebreyesus said at a press briefing.

More than 150,000 new cases were reported to WHO, nearly half of which came from the Americas, according to Tedros. Large numbers were also documented in South Asia and the Middle East.

"The world is in a new and dangerous phase," Tedros said. "Many people are understandably fed up with being at home. Countries are understandably eager to open up their societies and economies, but the virus is still spreading fast. It's still deadly, and most people are still susceptible."

Health officials report more than 8.5 million cases of the virus and nearly 455,000 deaths, according to Johns Hopkins University.

In the U.S., the Centers for Disease Control and Prevention is predicting up to about 145,000 deaths from the virus by roughly mid July.

The CDC reported in its forecast, which is a combination of data from more than 20 national models, a range of 128,719 to 144,795 fatalities by July 11.

Fatalities are expected to increase in Alaska, Arizona, Arkansas, Florida, Hawaii, North Carolina, Oregon, South Carolina and Utah, according to the CDC.

Health officials report more than 2.2 million cases of the virus in the U.S. and nearly 119,000 deaths.

If the CDC's highest projected death number plays out, the U.S. can expect to see more than 26,000 fatalities from the virus over the next roughly three weeks.


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20 Jun 2020, 7:01 am

The US is averaging about 700-800 a day. Getting to the 145,000 figure is probable, unless something drastic happens.



jimmy m
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20 Jun 2020, 7:58 am

One of the side effects of the virus - sleep deprivation.

As many Aspies are familiar with. Stress can produce anxiety and anxiety can result in a loss of sleep.

Many people are anxious these days because for he virus and now because of the demonstrations and riots.


“I took two Benadryl and still can’t sleep, I feel like I’ve hit a new low,” Christine Larochelle tweeted at 12:45 a.m. Tuesday. “Sunday night I was up ’til like 3 a.m. I was just tossing and turning, and nothing was helping me,” the 26-year-old who works in social media advertising tells The Post. “The moment I hit the bed and turn off the lights, my mind just races to everything that’s happened in my life.” Those weren’t off-nights for her. For the past few months, Larochelle has struggled with falling — and staying — asleep. She joins a horde of zzzzz-free zombies around the world who have been starved for a restful night since the coronavirus pandemic started.

Image

In the United States, 22% of people say that their sleep quality is worse because of the COVID-19 crisis, according to a survey done by SleepHelp.org.

Elsewhere around the globe, researchers also are harping on this nighttime uprising. One study published in April by the Journal of Critical Sleep Medicine found that insomnia and its symptoms drastically increased for COVID-19-free participants in China, the first epicenter of the disease, from January to February of this year.

In Italy, another major coronavirus hot spot, reports of decreased sleep increased more than 12% from February to March as the second week of lockdown kicked in, according to a study published in the Journal of Sleep Research.

Although the data suggests the world is having a sleep crisis, Dr. Alcibiades Rodriguez, the director of the sleep center at NYU Langone, says that we actually have an anxiety problem.

“Sleep is interconnected with mood and anxiety disorders,” Dr. Rodriguez tells The Post. “This is an unprecedented situation. It’s a high level of stress, especially in the middle of this in New York.” Trouble sleeping is actually a symptom of anxiety and depression, which he says are on the rise because of the pandemic.

“You’ll have tension, your concentration is decreased, your memory may be affected, you may be moody,” he says. “Suppose you have a medical condition, you have back pain or you suffer from migraines: You’re going to feel worse. If you feel that way, it may lead to more anxiety and more depression; it’s a vicious cycle.”

Although Larochelle says she hasn’t noticed a strong change in her moods, her migraines and headaches have gotten worse.

Source: Americans are having trouble sleeping because of coronavirus -- here are tips to help

[In reality, sleep repairs and resets the body. Two of the stages of sleep are critically important Deep Sleep and REM Sleep.

During deep sleep, your breathing, heartbeat, body temperature, and brain waves reach their lowest levels. Your muscles are extremely relaxed, and you are most difficult to rouse. Stage 4 is known as the healing stage, when tissue growth and repair take place, important hormones are released to do their jobs, and cellular energy is restored. Physical recovery takes place, blood sugar levels and metabolism balance out, your immune system is energized, and your brain detoxifies. Without deep sleep, these functions cannot take place and the symptoms of sleep deprivation kick in.

During REM sleep, Signals are sent to the brain's cerebral cortex, which is responsible for learning, thinking, and organizing information. Signals are also sent to the spinal cord to shut off movement, creating a temporary inability to move the muscles ("paralysis") in the arms and legs. The arms and legs become temporarily paralyzed during this stage to prevent a person from physically acting out their dreams and nightmares while sleeping. During REM sleep the eyes move around quickly behind your eyelids and your brainwaves look similar to those of someone who is awake. Breathing, heart rate, and blood pressure rise to near-waking levels. Electrical and chemical activity regulating this phase seems to originate in the brain stem and is notably by an abundance of the neurotransmitter acetylcholine, combined with a nearly complete absence of monoamine neurotransmitters histamine, serotonin, and norepinephrine. REM sleep stimulates regions of the brain that are used for learning. Studies have shown that when people are deprived of REM sleep, they are not able to remember what they were taught before going to sleep. So to put a long story short, without REM sleep, your short term memory buffers are not placed in long term memory and overflow and the body has a bit of a melt down.]


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jimmy m
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20 Jun 2020, 8:20 am

While health officials recognize that humans are, by nature, social creatures who crave interaction with others, the novel virus and its deathly effects are not exaggerated, as some have started to believe.

This week, states throughout the nation have seen surges in coronavirus cases, with the average number of new cases per day increasing by about 20 percent to nearly 24,000 cases per day. Health officials say a combination of factors is likely responsible for these increases. “It’s multifactorial,” said Dr. Janette Nesheiwat, family and emergency medicine physician and medical director of CityMD, said. “The initial wave of COVID-19 is still with us, hitting each state at different points in time. We see more cases because we are doing more testing. Also, the country is reopening, which means an increase in mobility of people, which by nature means we will have more cases.”

Image

Source: As states see coronavirus surges, health officials say combination of factors responsible

But then again, tracking the infection rate might be a little deceiving. So what is more important to me is the fatality rate due to the coronavirus. So here is that graph.

Image

Source: Our World in Data

So it looks like the coronavirus is winding down. But it may surge again in the fall and winter as the humidity levels fall below 40% again.


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jimmy m
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20 Jun 2020, 12:27 pm

ANTIBODY PLASMA TREATMENT

In a new study of convalescent plasma transfusions in 20,000 coronavirus patients, authors say the data offers “robust evidence” the treatment is safe and associated with improved survival.

The idea behind the therapy is that plasma of recently infected recovered coronavirus patients has antiviral antibodies that can be used to treat other patients with the virus.

“Convalescent plasma has a strong historical record of some efficacy during acute infectious pandemics,” study authors write.

The study, published on Wednesday in Mayo Clinic Proceedings, offered a larger analysis expanding on an initial report of 5,000 transfused patients. Patients were given the plasma through an expanded access program developed by the US Food and Drug Administration (FDA) and the Mayo Clinic.

Image

Between April 3 and June 11 this year, 21,987 COVID-19 patients received the plasma transfusions. Nearly all of the patients had severe or life-threatening COVID-19 conditions. The seven-day mortality rate dropped to 8.6 percent.

Source: Coronavirus plasma study shows 'robust evidence' of transfusion treatment improving survivability


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20 Jun 2020, 12:39 pm

That makes sense. A strong infusion into the body of something similar to “gamma globulin,” used to prevent symptom development of things like hepatitis.



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21 Jun 2020, 2:58 am

I can't help but this coronaviruspandemic combinated with the coming election makes me wonder how different american presidents or might handle a similar virus pandemic in the last two decades.

I have to say I'm not american so I can not see it like americans do so I guess that's why I'm wondering about this question.

Let's start from George W. Bush's second cycle. I remember I saw a documentaryfilm on the Hungarian National Geographic Channel or on the Discovery Channel about the biowarfare question which seemed to be a relavent question during the younger Bush's second political cycle. He used up the biological wepon queston as a reason to attack Iraq and remove Saddam Hussein from his leader post.
As I remember back in the second half of the 2000's politicians ment a possible Anthrax attack which would mean a human made virus pandemic with attacking determine.

Did the goverment back than had any real idea or plan to activate if that fear would come true or natural virus pandemic would hit the world back than?



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21 Jun 2020, 11:10 am

jimmy m wrote:
While health officials recognize that humans are, by nature, social creatures who crave interaction with others, the novel virus and its deathly effects are not exaggerated, as some have started to believe.

This week, states throughout the nation have seen surges in coronavirus cases, with the average number of new cases per day increasing by about 20 percent to nearly 24,000 cases per day. Health officials say a combination of factors is likely responsible for these increases. “It’s multifactorial,” said Dr. Janette Nesheiwat, family and emergency medicine physician and medical director of CityMD, said. “The initial wave of COVID-19 is still with us, hitting each state at different points in time. We see more cases because we are doing more testing. Also, the country is reopening, which means an increase in mobility of people, which by nature means we will have more cases.”

Image

Source: As states see coronavirus surges, health officials say combination of factors responsible

But then again, tracking the infection rate might be a little deceiving. So what is more important to me is the fatality rate due to the coronavirus. So here is that graph.

Image

Source: Our World in Data

So it looks like the coronavirus is winding down. But it may surge again in the fall and winter as the humidity levels fall below 40% again.


I thought about this anomaly last night. First of all, it is an apparent anomaly - the infection rate is still very high but on the other hand the death rate due to the coronavirus is dropping like a lead brick. This is my interpretation:

It is a function of viral load. During the winter the viral load in many areas were extremely high. A packed subway car in New York City may have had millions of viruses floating on a sealed train car. But now as the humidity levels rose above 40% RH and the as the sunlight became more prominent killing many of the viruses, the viral concentrations fell. People are still getting infected but their bodies are not getting overloaded. They have the precious time to build immunities and as a result even though they become infected, the symptoms are less severe and less deadly.

So what does that mean. Well from my perspective this is a very good trend. Over the summer and fall, many people will contract the disease, survive the disease and built antibodies to protect them in the winter when humidity levels again drop below 40% (the second wave). So in reality, the second wave will be substantially marginalized.

COVID-19 mortality is a function of viral load.


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21 Jun 2020, 12:15 pm

My take on the data is that younger people are getting infected. They are less likely to die.

I have no idea how this will play out in the fall and winter. Older people still die of the flu when flu shots are available in the winter months. I doubt there will be an effective flu shot for all the older people who need it this fall. Are there effective plans to stop the virus when it enters a nursing home? What can you do when you have nursing home workers that lack the ability to reliably carry out basis safety procedures? Retire them and put them on basic income?



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21 Jun 2020, 2:06 pm

I don't foresee N95 masks being available to the public for a long time. Maybe a year. Why do I think that? A few reasons:

>Medical community will take precedence in place of those gappy innefective paper pleated masks.
>Opportunists hoard anything available to price gouge and sell on the internet. As long as demand exceeds supply, they'll continue to do so.

When we'll actually be seeing N95 masks on home improvement store shelves with supply exceeding demand is a year or more in my opinion. Maybe it will be longer than that.

Covid is starting to spike in our county. It was around 120 for a long time. In the last week it's jumped to 142. I think it's going to kick in now.

I also think a second wave in the fall will kick in perhaps worse than the first.



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22 Jun 2020, 7:45 am

jimmy m wrote:
jimmy m wrote:
While health officials recognize that humans are, by nature, social creatures who crave interaction with others, the novel virus and its deathly effects are not exaggerated, as some have started to believe.

This week, states throughout the nation have seen surges in coronavirus cases, with the average number of new cases per day increasing by about 20 percent to nearly 24,000 cases per day. Health officials say a combination of factors is likely responsible for these increases. “It’s multifactorial,” said Dr. Janette Nesheiwat, family and emergency medicine physician and medical director of CityMD, said. “The initial wave of COVID-19 is still with us, hitting each state at different points in time. We see more cases because we are doing more testing. Also, the country is reopening, which means an increase in mobility of people, which by nature means we will have more cases.”

Image

Source: As states see coronavirus surges, health officials say combination of factors responsible

But then again, tracking the infection rate might be a little deceiving. So what is more important to me is the fatality rate due to the coronavirus. So here is that graph.

Image

Source: Our World in Data

So it looks like the coronavirus is winding down. But it may surge again in the fall and winter as the humidity levels fall below 40% again.


I thought about this anomaly last night. First of all, it is an apparent anomaly - the infection rate is still very high but on the other hand the death rate due to the coronavirus is dropping like a lead brick. This is my interpretation:

It is a function of viral load. During the winter the viral load in many areas were extremely high. A packed subway car in New York City may have had millions of viruses floating on a sealed train car. But now as the humidity levels rose above 40% RH and the as the sunlight became more prominent killing many of the viruses, the viral concentrations fell. People are still getting infected but their bodies are not getting overloaded. They have the precious time to build immunities and as a result even though they become infected, the symptoms are less severe and less deadly.

So what does that mean. Well from my perspective this is a very good trend. Over the summer and fall, many people will contract the disease, survive the disease and built antibodies to protect them in the winter when humidity levels again drop below 40% (the second wave). So in reality, the second wave will be substantially marginalized.

COVID-19 mortality is a function of viral load.


It seems that others are noticing this anomaly. Here is a news article this morning:

An Italian infectious disease doctor believes the coronavirus has become less dangerous — and could disappear on its own without a vaccine.

Dr. Matteo Bassetti, the head of the infectious diseases clinic at the San Martino hospital, said the virus appears to have become less potent, possibly due to genetic mutations, the Sunday Telegraph reported.

“The clinical impression I have is that the virus is changing in severity,” Bassetti told the outlet.

“In March and early April the patterns were completely different. People were coming to the emergency department with a very difficult to manage illness and they needed oxygen and ventilation, some developed pneumonia.”

But he said in the past month, “the picture has completely changed in terms of patterns.”

“It was like an aggressive tiger in March and April but now it’s like a wild cat,” Bassetti said. “Even elderly patients, aged 80 or 90, are now sitting up in bed and they are breathing without help. The same patients would have died in two or three days before.”

"I think the virus has mutated because our immune system reacts to the virus and we have a lower viral load...."

Source: Coronavirus weakening, may disappear on its own, Italian doctor says


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22 Jun 2020, 8:00 am

The grocery store had a kiosk with a supply of PPE, including KN95 masks.
The regular masks were sold in packages of 20.



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22 Jun 2020, 8:34 am

'No Evidence' Black Lives Matter Protests Caused COVID-19 Spike: Study

Quote:
A study using data from Black Lives Matters protests across 315 of America's largest cities found "no evidence" in the following two and a half weeks that they caused a spike in the number of new COVID-19 cases.

The paper, titled "Black Lives Matter Protests, Social Distancing, and COVID-19," also found "strong evidence" that the protests actually increased stay-at-home overall, likely because non-protesters chose to leave their homes less while the demonstrations were ongoing.

"This effect was not fully explained by the imposition of city curfews. Estimated effects were generally larger for persistent protests and those accompanied by media reports of violence," said the paper, published by the National Bureau of Economic Research.

As days of protest raged over police brutality against black people, sparked by the death in police custody of George Floyd, many public health experts expressed concern that the events could accelerate the spread of infection during the pandemic.

Though many protesters wore masks, and were outside, both factors that help to reduce the risk, social distancing was not widely adhered to, leading to warnings by health experts that the behavior may lead to a spike in new cases over the following days.

But authors of the study, which is the first to examine the links between the Black Lives Matter protests and COVID-19, said, "We find no evidence that urban protests reignited COVID-19 case growth during the more than two and a half weeks following protest onset.

"We conclude that predictions of broad negative public health consequences of Black Lives Matter protests were far too narrowly conceived."

Researchers used anonymous cell phone tracking data from SafeGraph, Inc. and local CDC data on COVID-19 to assess the impact of protests on social distancing, finding no evidence that they contributed to a net increase.

"These results make an important contribution not only to the current discussion around policies for controlling the spread of disease, but also to the understanding of human behavior of the general population during periods of civil unrest," the paper said.

The academics acknowledge a potential criticism that more time may be needed for cases related to the protests to emerge given the incubation period of COVID-19.

But they cited research showing the median incubation period is 5.1 days, with 97.5 percent of individuals experiencing symptoms within 11.5 days.

They wrote that "our sample includes at least 18 days of data following the early protests that took place in 66 cities (during the first four days following George Floyd's death), 16 days of data following protests in 202 cities, and at least 14 days of data for 240 cities that experienced protests (during the first week following George Floyd's death)."

The study is a working paper for discussion and has not been peer-reviewed. It was authored by Dhaval M. Dave of Bentley University's Department of Economics; Andrew I. Friedson of the University of Colorado Denver's Department of Economics; and Kyutaro Matsuzawa, Joseph J. Sabia, and Samuel Safford all of the Center for Health Economics and Policy Studies at San Diego State University. Newsweek has asked Dave and Friedson for comment.


Health Experts Link Rise In Arizona COVID Cases To End Of Stay-At-Home Order
Quote:

With new daily coronavirus cases rising in at least two dozen states, an explosion of new infections in Arizona is stretching some hospitals and alarming public health experts who link the surge in cases to the state’s lifting of a stay-at-home order a month ago.

Arizona has emerged as one of the country’s newest coronavirus hot spots, with the weekly average of daily cases more than doubling from two weeks ago. The total number of people hospitalized is climbing, too.

Over the past week, Arizona has seen an average of more than 1,300 new COVID-19 cases each day.

After the state’s largest hospital system warned about a shortage of ICU beds, Arizona Gov. Doug Ducey, a Republican, pushed back on claims that the health care system could soon be overwhelmed.

“The entire time we’ve been focused on a possible worst-case scenario with surge capacity for hospital beds, ICU beds and ventilators,” Ducey told reporters on Thursday. “Those are not needed or necessary right now.”

While he acknowledged a spike in positive cases, Ducey said a second stay-at-home order was “not under discussion.”

We put the stay-at-home order there so we could prepare for what we are going through,” he said.

Some states have reopened more slowly with a set of specific benchmarks for different regions, but Arizona took a more aggressive approach.

The state began easing restrictions on businesses in early May and lifted its statewide lockdown order after May 15. Under Arizona’s reopening plan, businesses are advised to follow federal guidance on social distancing.

There is also no requirement for everyone to wear masks in public.

Public health experts agree: The timing of this spike reflects the state’s reopening.

“Perhaps, Arizona will be a warning sign to other areas,” said Katherine Ellingson, an epidemiologist at the University of Arizona. “We never had that consistent downward trend that would signal it’s time to reopen and we have everything in place to do it safely.”

Before Arizona lifted its stay-at-home order, only about 5% of COVID-19 tests registered as positive. On Monday, that number was around 16%.

A slower reopening gives public health agencies time to identify whether cases are rising and then respond with contact tracing and isolating those who are infected.

“With a fast, rapid reopening, we don’t have the time to mobilize those resources,” said Ellingson.

Maricopa County, home to about 60% of the state’s population, has ramped up contact tracing in recent weeks, but it may not have enough capacity if the surge in cases continues.

Dr. Peter Hotez said the spike in Arizona, as well as in parts of Texas such as Houston, Dallas and Austin, is the consequence of removing restrictions too quickly and without a public health system that can keep pace.

“It was just ‘open it up’ and then more or less business as usual, with a little bit of window dressing,” said Hotez, the dean for the National School of Tropical Medicine at Baylor College of Medicine in Houston. “This is not an abstract number of cases. We’re seeing people pile into intensive care units.”

Arizona’s governor has also faced criticism from the mayors of Arizona’s two biggest cities for not putting in place more stringent requirements.

“There is a pandemic and it’s spreading uncontrollably,” said Tucson Mayor Regina Romero, a Democrat. Ducey, she said, “is just putting up his hands and saying ‘the spread is happening and we just have to go about our business.'”

And the governor’s executive order forbids local governments from implementing their own extra measures, which adds to Romero’s frustration. Texas has a similar measure.

“What he did was pretty much tie the hands of mayors and public health officials,” Romero said.

Arizona’s hospital industry has tried to tamp down fears that it’s on the verge of a crisis. Hospitals are still performing elective surgeries.

“It’s very unfortunate because hospitals right now in Arizona are quite busy with elective procedures,” said Saskia Popescu, a Phoenix-based epidemiologist with George Mason University. “You throw in increasing cases of COVID, and that’s going to very much stress your hospital systems.”

Phoenix’s triple-digit summer temperatures actually may fuel the spread of the virus. People forgo outdoor activities and retreat to air-conditioned indoor spaces, where the risk of transmitting the virus goes up significantly.

“My concern is we’re going to see a lot more people in close quarters for prolonged periods of time,” Popescu said.

Since the stay-at-home order was lifted, Popescu and others say they’ve seen people returning to a pre-pandemic mindset, neglecting to wear masks or maintain social distance. Videos of crowded bars have only propelled these fears.

On Thursday, however, Arizona’s top doctor stressed there were also dangers to keeping the state on lockdown, including the mental health effects of loneliness and isolation.

“We know that it’s in the community. We are not going to be able to stop the spread. And so we can’t stop living as well,” said Dr. Cara Christ, health director for the Arizona Department of Health Services.

But Dr. Quinn Snyder, an emergency medicine physician in Mesa, Arizona, said there needs to be more consistent messaging on public health measures like wearing masks.

“Frankly, I just think a wholesale reevaluation of where we’re at is critical right now, but I can tell you that we’re not doing nearly enough,” said Snyder, who has seen the uptick in seriously ill COVID-19 patients firsthand.

“If we continue to head down this path, the virus will press our health care facilities beyond capacity, where we’re going to have to be making tough decisions like who gets a ventilator and who doesn’t.”


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Last edited by ASPartOfMe on 22 Jun 2020, 8:42 am, edited 2 times in total.

kraftiekortie
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22 Jun 2020, 8:38 am

Most of the protesters....even most of the cops...were smart enough to wear masks.



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22 Jun 2020, 8:39 am

BTDT wrote:
The grocery store had a kiosk with a supply of PPE, including KN95 masks.
The regular masks were sold in packages of 20.


When worn properly (with the mask making a tight seal with the user’s face), surgical N95 masks can filter at least 95% of very small (0.3 micron) test particles, protecting against hazardous airborne contaminants, including dusts, fumes, mists and microbial agents such as tuberculosis bacteria & viruses.
---------------------
KN95 masks were produced in China and millions of them have been bought or donated to American hospitals for healthcare works on the front line of the COVID-19 pandemic, the NYT found. [You might think of them as an N95 knock-off.]

The Centers for Disease Control oversaw testing of KN95 masks beginning in mid-April, the results of which found that some of these products do not meet medical standards for protection against the coronavirus.

The CDC and the FDA began their own review of KN95s as a precaution, and the FDA announced May 7 that too many of the masks failed to filter out an adequate percentage of particles. Of the roughly 11 masks that the FDA approved for sale to U.S. hospitals, seven failed testing. In one test conducted by the CDC on April 15, one mask filtered as little as 24-35 percent of particles.

However, it wasn’t until May 7 that the FDA banned more than 65 of the 80 authorized manufacturers in China from exporting KN95 masks to the U.S.

Source: FDA bans use of some KN95 masks weeks after failed testing


_________________
Author of Practical Preparations for a Coronavirus Pandemic.
A very unique plan. As Dr. Paul Thompson wrote, "This is the very best paper on the virus I have ever seen."