Oh yes, definitely. That happens to me pretty much all the time. Growing up, I really wasn't fully aware of it, or why people treated me the way they did, since I wasn't aware of my strangeness at the time. I liked myself back then, because I was oblivious.
Now that I've learned about AS and its characteristics, I know it's my mannerisms and my eye contact that make me seem odd, I suppose it's a natural reaction from the majority of "normal" people. I suffered terribly from rejection after rejection from people I formed attachments.
I've had to come to terms with it, since it's something I can't change. I realize I'm not going to be like the majority of people, ever. In accepting that, I found it rather liberating. I started liking myself again.
It's like being born a mutant or something. You focus on your inner strengths, and develop yourself to where you accept yourself along with your imperfections, because in reality, everyone has some sort of fault or imperfection, it's just some learn to hide it better than others.
This society I live in for example, thanks to the influx of mass media and its unrealistic expectations, seems to be obsessed with being perfect, in appearance, intelligence, mannerisms, etc. People as a result are hyper-critical, and quick to express their criticisms with one another. Therefore many people learn to be overly self critical and miserable.
Then the self help industry makes a mint trying to help people convince themselves to accept themselves and their differences, and in turn to accept others and their quirks. The world is a strange, imperfect place, and too many people don't seem to notice their own weirdness.
I suppose if you are surrounded by people with similar "weirdnesses", then it will come across as "normal". LOL
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Never assume you know what I'm thinking, just ask for clarification.
"Not everything that steps out of line, and thus 'abnormal', must necessarily be 'inferior'. " -- Hans Asperger (1938)