Harder compared to who? An average, healthy NT? Most likely yeah, but there are other conditions besides asperger/autism that can make certain things in life a lot harder. Someone with just asperger/autism might have it way easier doing some things than some people with certain physical disabilities or other neurological conditions. For examble, I've heard that it's really hard for those who are mentally behind to get a job, even if they could do a simple job that mostly needs physical power and stamina.