I use a mattress cover that is bedbug proof and allergen proof etc on the new queen sized mattress I bought last summer. I use a cover on both of my pillows as well underneath the pillow cases so hopefully that helps with my allergies. I also ripped out all the carpet and replaced it with lamanent flooring, and threw out 95% of all the stuff from my room so it is easier to keep clean, so my allergies aren't as bad. Oh and I run a HEPA filter tower in my room every night, which doubles as whitenoise to help me sleep.