Oxytocin Autism Treatment
This needs to be investigated for schizoid personality disorder, not autism.
Oxytocin doesn't necessarily have that effect. In one of the many studies that has been done on it, they tested behaviour when people don't have enough information. Instead of being more trusting, people were less trusting, in other words, they acted less gullibly. But this was just one study - those results might not be replicable, or they might, who knows til someone does the work.
The more important point is one that Cockney Rebel makes: some, many or even most people with autism spectrum conditions don't want to change or be changed. It's that medicalisation discussion again.
Then I'd love to at least try it. I don't understand anyone who doesn't want to change or enjoys the problems associated with being autistic, not including the assets of course like talents, special interests and focus.
Can you understand wanting to be your introverted self instead of someone else? Because that's why I wouldn't try it, even if it worked--I don't want to desire more human contact, and I would rather communicate in words than worry about faces and gestures. I'm happy as an introvert. I don't want to suddenly desire human contact all the time.
If the focus I have on my special interests suddenly got switched to other people, it wouldn't help me a bit. And, y'know, that feeling people describe when they're cuddling their cat or an infant? Yeah, I get that with cats and babies. I also get it when I'm fascinated with a special interest. I do NOT want to be that fascinated with random people. It would just set me up for a lot of pain.
Oxytocin wouldn't change that you're autistic. We already know that autism is in the structure of the brain. So, basically, what you have, in the ideal situation where this stuff actually works, is an autistic person who wants human contact, feels connected to others, mimics emotions and reads faces better than he used to... and is still odd enough to be utterly rejected.
Before we make use of a medication that lets autistics want to be with other people and read faces better when they are talking, we'd better solve the problem of those other people treating us like dirt whenever we try.
I'm willing to bet that a lot of the hoopla about oxytocin is due to the general public's idea that "loners are freaks"--i.e., that it's not normal to be introverted. But there's nothing wrong with being introverted; it hurts nobody and it causes no distress and that means they need to STOP pathologizing it.
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Last edited by Callista on 23 Jan 2010, 5:18 pm, edited 3 times in total.
Oxytocin is a hormone. The drug forms are pitocin and another which escapes me.
I also had failure to progress in labor with my first and was given pitocin. I did not experience anything like what the previous poster experienced. In fact, it had no mood altering affects to me (then again, when you're in hard labor, you aren't exactly noticing this crap).
However, the effect of naturally occurring oxytocin when I was breastfeeding an infant? That was a very lovely feeling I will always miss - all tied in with having a new baby. If biology didn't pay women off for nursing an infant, none of us would do it because it's tremendously difficult and at first none of it feels natural. You sit with the baby, and feel so happy and content warm feeling. It is just a calming feeling. Oxytocin is tied to bonding, and it's released with orgasm (more with a partner-involved orgasm than masturbation too, I read).
My guess is the effects from something like this properly administered in a very low dose would be subtle. In naturally occurring amounts this is not a mind-blowing-mood-altering experience, like a pain pill would be.
(edited to correct idiotic misspellings).
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Last edited by BetsyRath on 23 Jan 2010, 9:37 pm, edited 1 time in total.
[picky]
Betsy--it's spelled "oxytocin"--FYI. Oxycontin is a completely unrelated painkiller.
[/picky]
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If the focus I have on my special interests suddenly got switched to other people, it wouldn't help me a bit. And, y'know, that feeling people describe when they're cuddling their cat or an infant? Yeah, I get that with cats and babies. I also get it when I'm fascinated with a special interest. I do NOT want to be that fascinated with random people. It would just set me up for a lot of pain.
Oxytocin wouldn't change that you're autistic. We already know that autism is in the structure of the brain. So, basically, what you have, in the ideal situation where this stuff actually works, is an autistic person who wants human contact, feels connected to others, mimics emotions and reads faces better than he used to... and is still odd enough to be utterly rejected.
Before we make use of a medication that lets autistics want to be with other people and read faces better when they are talking, we'd better solve the problem of those other people treating us like dirt whenever we try.
I'm willing to bet that a lot of the hoopla about oxytocin is due to the general public's idea that "loners are freaks"--i.e., that it's not normal to be introverted. But there's nothing wrong with being introverted; it hurts nobody and it causes no distress and that means they need to STOP pathologizing it.
Like any drug, the effects are limited in duration. I have trouble communicating in words and doubt the drug would even help me because of it. I would try it just to see what it felt like to 'want' to be social. My guess is I would have some terrible side-effect and I would still be stuck with my verbal communication challenges so it wouldn't work for me anyway and probably even be agonizingly frustrating in combination with my hypersensitive sensory issues. I would just like to know what it feels like to be an average person with average social skills for a minute, but I doubt any drug could really do that for me anyway. I have tried other drugs that were prescribed to me a few times and dealt with the rather severe adverse reactions and side-effects and lived through it. This drug sounds intriguing so I would at least give it a single try once I understood what I could expect in the way of side-effects and other potential risk factors and if I were comfortable with those things then I would try it at least once.
I'll have to admit that it's encouraging to me that this would be a temporary effect. But you've got to remember that a lot of this stuff will be used on kids, if it turns out to work; and that means the same kids who are kept on stimulants or antipsychotics for years when it isn't actually helping them, and actually hindering their learning. This has a bigger potential for abuse even than those drugs, because you might get a quiet, zombie-like kid without behavior problems on antipsychotics, but if oxytocin really makes you want to interact, but has other effects that are harmful, the parent may keep the child on the drug just because the child now gives the parent the emotional fulfillment they have expected of him. That is a dangerous precedent to be setting. Children shouldn't be drugged because their parents want to feel loved; but you know that some of these curebie moms will be doing exactly that.
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I am against meds in general since they don't really solve the problem but mostly drug the person in a way that it compensates for some portion of symptoms.
This being said, I think this drug is definitely better than others since, most drugs work on some SIMPLE issue like attention span or mood, and HOPE that these simple issues will affect some aspects of complex problem. On the other hand, the drug you described sounds like it adresses complex issue directly, since it is not known to make you happier or more focused; rather it makes you more social, period. And that is despite the fact that socializing is really a very complex phenomenon. Now isn't this, by itself, amaising?
Now like I said I am against all drugs. But if you want to try some, I would say this one would be far more reasonable than antidepressants/antipsychotic/stimulant ones.
I'm totally against drugs where it isn't a life sustaining necessity, of course. This drug sounds interesting but I'm highly skeptical it would really be that effective or useful in the first place. And you can't do anything about all the wannabe's or "curebie mom's" of the world so, whatever.
Betsy--it's spelled "oxytocin"--FYI. Oxycontin is a completely unrelated painkiller.
[/picky]
I knew that, and probably it was Freudian since I was annoyed with the mistake above in someone else's post. So, touche to me! Not picky, valid.
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Also - I am highly non-interventional when it comes to any medication. And maybe I'm picking my own nit here but wouldn't it be hormonal therapy instead of drug therapy?
All I know is, maddening as he can be sometimes (me too, I'm sure) if someone changed my aspie husband to make him all warm and gooey, I would hate it.
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Oxytocin is injected into livestock (and sometimes people) to hasten or cause stronger labor contractions. It also "makes the milk come down"...lactation.
heh
It is naturally released as well, when babies are nursing, as well as other times. It is, indeed, a hormone. Seems bizarre though, that it would be used to treat those on the spectrum. Can you imagine?
"Yeah...I don't have meltdowns anymore, but I have to wear a special bra with absorbent pads in it, because my meds make me lactate."
heh
It is naturally released as well, when babies are nursing, as well as other times. It is, indeed, a hormone. Seems bizarre though, that it would be used to treat those on the spectrum. Can you imagine?
"Yeah...I don't have meltdowns anymore, but I have to wear a special bra with absorbent pads in it, because my meds make me lactate."
People would probably think I look pretty strange with one of those on.
That's the bad news. I'm sure I read that the oxytocin did seem to move people along the systemising-empathising axis. But you never know.
And that's a good example of how misleading one anecdote can be. Maybe I was just delirious and it was nothing to do with the syntocynon (oxytocin).
Oh by the way, I looked it up and found out that clary sage may induce seizures in epileptics and mania in bipolar sufferers. There may be other side effects too.
Bumping this discussion because I spotted this today when I logged onto MSNBC:
‘Love’ hormone may help autism symptoms
Study suggests oxytocin fosters eye contact and social behaviors
WASHINGTON - A hormone thought to encourage bonding between mothers and their babies may foster social behavior in some adults with autism, French researchers said on Monday.
They found patients who inhaled the hormone oxytocin paid more attention to expressions when looking at pictures of faces and were more likely to understand social cues in a game simulation, the researchers said in the journal Proceedings of the National Academy of Sciences.
Angela Sirigu of the Center of Cognitive Neuroscience in Lyon, who led the study, said the hormone has a therapeutic potential in adults as well as in children with autism.
"For instance, if oxytocin is administered early when the diagnosis is made, we can perhaps change very early the impaired social development of autistic patients," Sirigu said in an email.
Sirigu said the study focused on oxytocin because it was known to help breast-feeding mothers bond with their infants and because earlier research has shown that some children with autism have low levels of the hormone.
People with Asperger's syndrome and other autism spectrum disorders often have problems with social interaction.
Eye contact the first step
Sirigu said oxytocin could help autism patients who have normal intellectual functions and fairly good language abilities because it improves eye contact.
"Eye contact can be considered the first step of social approach," Sirigu said. But people with autism often avoid looking at others.
"In our study we show that oxytocin enhances eye contact because patients spent more time looking at the eyes," she said.
She said the hormone also improves the ability of people with autism to understand how other people respond to them, and they can learn the appropriate response to others' behavior.
In their study, Sirigu and colleagues had 13 people with high-functioning autism spectrum disorders inhale oxytocin before taking part in two experiments.
The participants, 11 men and two women, had no medication two weeks before the study, which included a control group of an equal number of healthy men and women.
The researchers watched the patients' responses during a virtual ball tossing game to measure behavioral changes.
In a separate experiment, Sirigu's team measured how patients responded to facial expression when shown pictures of human faces.
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