Do you find pain killers dont work?

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I suffer from chronic basilar / vestibular migraines. The pain isn't alwas the cardinal symptom (the most debilitating symptom I have is, when I have a migraine, being so giddy, disorientated and vertigo that I walk around like I'm very drunk, staggering about, have been stopped in the street before when this has happened). But I do get migrainous pain. Paracetamol does absolutely nothing for the pain, but dihydrocodeine does. However dihydrocodeine gives me severe constipation and drowsiness even at low doses, and it is not for chronic use. So I usually end up waiting it out with a cold pack on my head, laying in a dark room.

However paracetamol does work for my menstrual pain.

The Ibuprofen Liquid Gels seem to work for general muscle aches. Tylenol does reduce my occasional light headaches.

Hydrocodone (for a root canal) did the trick or at least made me feel so good I didn't care about the pain.

Male 52 years Diagnosed with AS.

I very rarely get any form of relief from pain medication; the exception being Migraleve which does take the sharp edge from the pain but still leave the dull ache underneath. For the main part I drink caffeine and try and get some fresh air; if that fails I simply just try and push on through.

I have had chronic head aches for the majority of my life, along with neck and shoulder pain and have all the tests imaginable but there is nothing they can pin it down to.

Given that the autistic brain has been shown to have more connectivity than other brains, I have always assumed that this would bring with it greater activity and therefore more potential for potential pain. That said, the brain has fewer pain receptors than other parts of the body but the hypersensitivity and complex wiring may account for the constant pain.

Advil and Tylenol work fine for me, though it could be a placebo effect too, since they sometimes take a while to kick in.

Advil is hard on my stomach so i never take it. I usually take Aleve instead & find it helps some. Asprin helps my headaches but that's the only reason I take it. Tylenol also helps my headaches but it's not as good as Asprin but the two work better together.. I took Oxycodone & Tylenol after a surgery & I only needed to take one Oxy at a time instead of the two like I was prescribed & it wasn't hard on my stomach like Advil is.

Paracetamol does not work unless with Codeine ie Co-Codamol/Kapake. Tramadol is no good either. Aspirin works for a short while if 3 taken but gives me stomach ulcers as does Ibuprofen.

Bupe works as does Morphine Sulphate. Gabapentin was no good either or Amytryptilene

I have Chronic Regional Pain syndrome and have been implanted with a spinal cord stimulator since 2009 so this helps control pain without these opiates which made me very drowsy and constipated

I became addicted to these and had to come off them very slowly to avoid cold turkey which is not nice at all

they work for me, i just dont like taking pills, i have no reason or exuse, i just dont like it

Tylenol works for me.
I haven't taken much painkillers in my life, only Tylenol for a sore throat when I have a flu.
Tylenol not only kills the pain, but also makes me drowsy and sleepy, and when I wake up, I am happy.

Gabapentin and betahistine do very little for my migraines but I'm not due to see my neurologist until the 9th of April. I have to drink 2-3 litres of water a day to stop myself from being semi stuporous from migraines. I eat extra salt to prevent hyponatraemia. I was in A&E recently for a severe migraine that presented like a stroke.

I have chronic pain, joint problems and endometriosis, and I'm autistic. I'm in pain almost all the time, but usually it's tolerable. When it becomes unbearable, I take 2 extra strength acetaminophen, which often help. After an hour, if it's not working though, I take a meloxicam, which I have a prescription for. Occasionally, after another hour, it's still not working, so I take a tramadol, which I have a prescription for. I haven't found a way to make my pain go away completely, I'm only trying to get to a point where it's tolerable. The tramadol usually does that. Before my pain got bad enough for prescription pain meds, I would take 2 extra strength acetaminophen, and then 2 extra strength ibuprofen after an hour for most things. For the endometriosis (this was before it was diagnosed and before I was on medication for it), I had to take 2 extra strength ibuprofen at the very first twinge of pain or when I predicted I was about to be in pain (which I can do because it's cyclic). If I took it BEFORE hurting, I would hurt hardly at all. But, if I waited until I actually started hurting, the ibuprofen did absolutely nothing, nor did acetaminophen. When the pain got bad enough that I got on prescription pain meds, my doctor originally prescribed hydrocodone. I found out real quick that hydrocodone has absolutely no effect on me, good or bad. I don't have any of the side effects, and it also does absolutely nothing for my pain. So, now he gives me tramadol; which, like I said above, makes the pain tolerable. My psychologist tells me that this is very common for autistics. He says that some anti-anxiety medications can help some autistics with pain when pain meds don't work, but I haven't tried them.