I freely admit I'm not being scientific in my thoughts on this, because my sample size is 1. My reaction to Baron-Cohen's theory is based solely on myself (as a female dx'd w/AS)-have never knowingly met another aspie.
I bought his book "The Essential Difference" & took the systematizing (SQ) & empathizing (EQ) self-tests included. Then I had my (NT) boyfriend take those same tests. Results: He was both high systematizing & high empathizing. I was very low on both dimensions. Doesn't sound like whatever the expected results would be to me.
I'm neither particularly masculine nor feminine overall (mentally), it depends on what's being measured. In specific ways, I'm more one or the other. Personally, I don't find his theory explains much of anything about how I am-and I felt this way before taking the SQ & EQ quizzes. However, I wouldn't presume to try to talk anyone else out of it, if this "works" for them.
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*"I don't know what it is, but I know what it isn't."*