Hypersensitivity - to drugs e.g. caffeine also?

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Painkillers are fun also, aspirin and paracetamol do not work properly, I need lots of them to notice something. Ibuprofen is great however, it works and makes me feel happy. (it would be suitable as a recreational drug for me)

Caffeine makes me sleepy...but I am addicted... I self-medicate with stimulants like caffeine and such to help me focus...and sometimes I overdo it...but I never quite feel like I have enough stamina. I might get irritable though...

The effect of alcohol on me is dependent upon my previous mood...it will either take the edge off and allow me to cope more easily with my surroundings, or set me up for a meltdown...

um....Marijuana can break down the whole structure of my mental stability...sometimes for a few days..on just a very small amount. I can totally regress in unpleasant, disturbing and uncomfortable ways. It is a harsh reminder that I am not as "together" as I think i am and have serious underlying unresolved issues.
It is the only thing I can think of that I am really hypersensitive to.


I wish there was something that could make me feel light and giddy...but I don't really get that from anything.

I'm definately sensitive to caffeine in a way. It has an effect on my motor function. I'll have trouble walking and doing simple stuff. I don't know if it is noticeable to others but it feels kind of like the muscles are more relaxed and/or tense and it's harder to control them. All this from a normal size dose. I hate it.
I googled the effects quick and they do happen, although I don't know if it's common to have such a difficulty with them. Also I seemed to get ridiculously amped up from a tiny amount of speed so maybe it's stimulants in general. Can't think of anything else having an uncommon effect.

Many drugs and stimulants don't seem to have any effect on me. My father had the same "problem."

paracetamol and aspirin have never killed pain in me. Ibuprofen usually helps, though it did nothng to ease a recent bout of headaches. When I broke my leg they gave me a shot of morphine, and that worked very well.

Tea and coffee I drank to excess for years - I felt no effect at all, though when I began to get an annoying twitch in one eye, I switched to decaffeinated and the twitch stopped. A lot of people said the caffeine withdrawal might give me terrible headaches, but that never happened. I took a load of caffeine tablets once, and got palpitations, which I didn't like at all.

Alcohol kind of "works" though it's never made me lose control.....more like I know I have an excuse to be a little more extravert. It does reduce my inhibitions a little, so I might say what I think more readily, without stopping to consider the effect. It makes me feel woozy and gives me a headache the morning after unless I drink a lot of non-alcoholic liquids before bed.

Beta-blockers seemed to have little effect on my anxiety, though I stopped taking them after a few days.

Chocolate and sugar don't seem to stimulate me. I went through a phase when I was eating about 300g a day. It was very comforting but after a few weeks I started to feel really ill, so I stopped.

Cannabis used to make me feel great, and seemed to drive up my intelligence, but its effect seemed to get less and less over the years. I was smoking it so regularly that it became hard to know what it did, because I was never off it. Certainly I was functioning quite normally as far as I could tell. When I did stop, I also stopped smoking tobacco, and took up the use of a hot nicotine delivery system instead. I had no noticeable physical withdrawal symptoms for the first couple of weeks, then I got a bad bout of terminal insomnia and hypertension for a week or two, but the cause of all that is still a mystery, and could have been down to a few stressful events that happened at the same time - like my mother (who never did drugs), I've always been prone to physically react very acutely to some stressful situations, though only those who are close to me would notice anything wrong. I was able to play through the pain without harming myself or others. It's possible that cannabis was easing some of my AS symptoms, as there's some evdence that they're now getting slightly worse. But I can't say I feel all that different, and I haven't touched a joint or a cigarette for 3 weeks now. I got a lot of headaches (and ibuprofen wouldn't stop them), that's common in people who quit smoking, because the blood oxygen levels rise.

Magic mushrooms worked very well on me if the dose was reasonably high, though I never had any hallucinations as such. I was always careful to avoid taking them very often, and haven't had any for many years.

looks like a pretty mixed picture!

Alcohol - My face gets flushed and I get heated from my first drink. I'm mildly buzzing by the second, if I make it to 3, then I MUST be having a good time and looking to get drunk.

Marijuana - I've enjoyed it more in my own company than I have being around others. In my late teens it threw me into many panic attacks.

Oxycet - Took this once for pain. Took one pill. 10 minutes later, while at the computer, the screen went all fuzzy, I couldn't focus on anything and became nauseous. I remember hitting the computer power button and running for the bathroom. I threw up, then went and laid down and slept it off. Yuck! ...never touched another one.

Benelyn Daytime - This drug dries up my sinuses and pretty much makes me feel super focused. It makes my heart race, gives me goosebumps and scalp tingling. Weird.

Antihistimines = panic

Nitrous Oxide (laughing gas) - has rendered me unconcious.

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My son

Benedryl - spun him out SO bad when he was two, that I seriously thought something had snapped! Made him extremely hyper, running like a little madman through the livingroom, then through the kitchen, and back through the livingroom again! I've avoided giving him antihistimines since. Thankfully, he isn't allergic to anything that I know of.

Stimulant Medicines (Concerta, Adderall) - these cause him to tic like crazy. Facial grimacing, raising eyebrows repeatedly, looking up and to the right, cracks knuckles and joints like crazy.

The alternative (Strattera) - is currently making him nauseous, giving him headaches, making him extremely tired and irritable, also he's more emotional than he's ever been, there's a lot more thought put into the things he's getting emotional about. None of which I'm too impressed with.

Nitrous Oxide - Laughing gas at his last dentist appointment (which is already traumatic enough due to immense sensory issues) sent him into a full blown panic attack. He was so scared, scared of how he felt. He kept trying to get up and the dentist had his hand on his shoulder.... I finally snapped "Book us at the HOSPITAL!" at the dentist, because now my senses were all fired up, watching him assume that restraining someone who's panicking is a GOOD idea... get real!

Even the Melatonin we tried for sleep issues seemed to have a really exaggerated effect on him, at less than half of the recommended dose.

I think he and I are both quite sensitive. Coffee makes me twitchy, but I'm addicted.

Me too, come to think of it. I enjoyed the ritual of passing the reefer round the circle of friends, and did a lot of that, but found it annoying to have to wait so long for my turn for a toke to come round again. So I'd often stay in my room and smoke away, thinking, writing, composing music and playing my guitar It kind of worried me because I'd read that one of the signs of alcoholism was drinking alone, so I feared it might be a sign I was going down some kind of slippery slope to narcotic oblivion. But no, I was just doing my usual "lone wolf" thing, and being a tad greedy and antisocial.

Most drugs work as intended on me, but I remember when i was on Ritalin, it was weird. Unless I had caffeine and sugar (I've always liked tea, and as a kid, sugared cereal is a standard breakfast), it would have the exact opposite effect desired. My teachers would comment that I was bouncing off the walls. Now, if only the doc hadn't prescribed that drug in the first place, I might have physically developed a bit more normally, and not put on quite as many pounds. (I really packed on the pounds after I was out of high school, thus off Ritalin. I think I never learned to eat right because of it's appetite supressing side effects. It also delayed my going through puberty as well.)

I don't feel caffeine unless I drink 2 cans of energy drinks...
Weed hits me normally I think...
I need to drink more to get drunk or buzzed...

So basically I'm less sensitive to caffeine and alcohol.

Alcohol - even a tiny sip turns my face red
Caffeine - makes me sleepy
Antihistamine:
chlorpheniramine - makes me hyper. It keeps me from sleep but dulls my thoughts
Zyrtec - I tolerate it much better. Very mild diarrhea occationaly. Somehow I could get by with 5mg every other day.

Other than being a bit more clumsy than usual, I'm known for seeming relatively sober after large amounts of alcohol.

Marijuana, well...

I used to smoke and listen to music on a daily basis.

I have extreme hypersensitivity in regards to my hearing.

As I was listening to music, I could hear instruments and melodies that weren't actually in the song I was listening to. I thought at the time that I was hearing subtle harmonic overtones or resonances that weren't normally audible to the human ear. Or something. It would be impossible for me to try to attempt conversation, if I was with people.

Needless to say, people though I was strange.

It was weird, but awesome in a way.

Coffee - I avoid it because it makes me jittery.

Alcohol - My first mouthful brings muscle aches and goes to my head soon after. I know this because I'll start snickering or something.

Paracetamol - I only need one tablet to feel an effect and it gets rid of any headache for good.


The above are probably influenced by my relatively light frame.