I don't personally have a problem with letting people know about my condition, just as long as they're controlled to people who I trust. I've told most of my immediate family, some of my co-workers, and several people at church I associate with regularly. As far as making a grandstand announcement about it to everyone on FB or in church, I try to refrain from that.
The only person who I've decided to not tell is my grandmother. While she's caring and in relatively good health, my family and I have agreed that she'd probably have a difficult time wrapping her mind around the news. So unless some odd occasion were to arise, like the rest of the people I haven't told, it's something she simply doesn't need to know.
Even though I don't make many new friends these days, I'm still undecided on how to handle telling them about my condition. Even though I've never had a girlfriend, I can imagine I would have to let her know fairly early on in the relationship in order to minimalize awkward moments. Besides, I'd rather her accept me for what I am than have her think I might be just another one of those "nice guys."