Twilightprincess wrote:
firemonkey wrote:
Differentiation between autism and multiple complex developmental disorder in response to psychosocial stress.
Jansen LM1, Gispen-de Wied CC, van der Gaag RJ, van Engeland H.
Author information
Abstract
Multiple Complex Developmental Disorder (MCDD) represents a distinct group within the autistic spectrum based on symptomatology. Unlike autistic children, part of MCDD children develop schizophrenia in adult life. Despite the differences, patients of both disorders are mainly characterized by abnormal reactions to their social environment. At the biological level, we showed in a previous study that MCDD children have a reduced cortisol response to psychosocial stress. Given the fact that autistic children clinically show more social impairments, it was hypothesized that they may have even further decreased cortisol responses to psychosocial stress than MCDD patients. Therefore, 10 autistic children were compared to 10 MCDD children and 12 healthy control children in their response to a psychosocial stressor, consisting of a public speaking task. In order to test whether any impairments in the biological stress response are specific for psychosocial stress, the autistic children were compared with 11 MCDD children and 15 control children in their response to a physical stressor, consisting of 10 min of bicycle exercise. Heart rate and salivary cortisol levels were used as indicators of response to the stress tests. Autistic children showed a relatively elevated cortisol response to psychosocial stress, in contrast to MCDD children who showed a reduced cortisol response. No differences in heart rate or cortisol responses to the physical stress test were found. The specific difference between autistic and MCDD children in their cortisol response to psychosocial stress indicates that the disturbed reactions to the social environment observed in these disorders may have different biological backgrounds.
https://www.ncbi.nlm.nih.gov/pubmed/12629541That’s a pretty small study. I think there needs to be more research for it to be given diagnostic validity.
True. I fully agree more research needs to be done for it to be confirmed as a diagnosis.
This is the criteria that has to be met to get in the DSM based on an article from 2006 (My bold)
To make it into the DSM-V, a new disorder will have to meet a host of criteria.
Its symptoms must be severe enough to cause impairment or distress (a possible deal-breaker for one proposed diagnosis, caffeine withdrawal disorder).
New diagnoses must also be sufficiently different from categories of illness already recognized by the manual. Pathological grief disorder, for example, characterized by prolonged and excessive anguish following the loss of a loved one, is a strong contender for inclusion in the DSM-V. Its supporters must conclusively show, however, that it is distinct from similar conditions, like major depression.
Advocates of a new diagnosis must also demonstrate that it won't generate false positives—people who meet the diagnostic criteria but don't actually have the condition. That could be a problem for binge eating disorder, a diagnosis that has generated significant research but might apply to a disconcertingly large proportion of America's overweight population.
Disorders that are judged to be politically sensitive may also come in for added scrutiny.That was the case for masochistic or self-defeating personality disorder, a DSM-IV candidate that was scrapped when critics objected that it might be used to suggest that victims of violence invited or enjoyed being abused. Likewise, premenstrual dysphoric disorder was proposed for inclusion in DSM-III and again for DSM-IV but was relegated to the "for further study" appendix after protests from women's groups, who said that the category treated a normal biological function as a pathology.
http://www.slate.com/articles/news_and_ ... rozac.html"Sufficiently different" might be a tall hurdle to overcome. MCDD might give a short hand descriptor for people like me with self described ASD traits + schizotypal traits +probable /dyspraxia/learning difficulty/NVLD + probable avoidant but is that sufficient to warrant its inclusion as a new diagnosis?
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Socially drifted middle class
05 Aug 2018, 8:35 pm
