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Nightmare on the boulevard at dawn.
Sounds like a good book.
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So I arrived home seriously wanting a sedative (or something) to take before going out. I guess it doesn't help that they're fixing the garage *and* the roof of my building, and they've been drilling from 9am to 5pm for a month. So maybe I'm already up to semi-rattled even before I go out.
Well, that is enough to drive anyone mad. No wonder. Your nerves must be shot.
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re something - a pill or a cup of tea or a funny cigarette - that would turn me into a zombie for an hour?
Why only an hour?

I wouldn't know about funny cigarettes.

I try to stay away from weird tea because in my experience I have had adverse reactions, making me more jumpy and hyper, sometimes extremely so where I have to pace or run around the yard in circles to work it out of my system.

Seriously though, IMO, it would be better to be able to address sensory issues without any substance outside of yourself if possible, although sometimes I can understand how a sedative would be necessary. What about Yoga? I know, everyone says "What about Yoga?" But really, controlling your mind, mental activity, thoughts has been proven to do wonders for restoring health and wrecked nervous systems.
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I know there are gizmos than can reduce individual senses, and I have some, but how can I become oblivious?
You can only become truly oblivious when you cease to exist. In the meantime, I can recommend two books. These are not written by Autism "specialists" as far as I know, but they really address and offer great advice for the problem of extreme sensitivity.
1. "too loud too bright too fast too tight" by Sharon Heller, Ph.D.
2. "The Highly Sensitive Person" by Elaine N. aron, Ph.D.
Also, Izaak's advice is excellent. Where can we get those Irlen lenses Izaak, and can we get them without a doctor's prescription? Are they expensive?
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Auditory: Earplugs (Mp3 players some times work)
Visual: Sunglasses or Irlens glasses
Touch: special clothes have been designed for those.