Is anyone else A topic ? (AS people only please !)
Signs and symptoms
Patients with atopic eczema usually develop what is referred to as the “allergic triad” of symptoms i.e., eczema, hayfever, and asthma. They also have a tendency to have food allergies, and other symptoms characterized by their hyperallergic state. For example, eosinophilic esophagitis is found associated with atopic allergies. Atopy and atopic eczema can be considered a genetic disease because of its strong genetic component, but atopy does not segregate like an autosomal dominant trait. There are certain environmental factors that contribute to its appearance in infants and children, but the underlying cause is a genetic tendency to be hyperallergic. Atopic eczema cannot be prevented in infants because of its genetic origins.
Atopic syndrome can be fatal for those who experience serious allergic reactions, such as anaphylaxis, brought on by reactions to food or environment.
The individual components are all caused at least in part by allergy (type I hypersensitivity reactions). These responses appear after the body is exposed to various allergens, for example specific kinds of food, pollen, dander or insect venoms. Although atopy has various definitions, most consistently it is defined by the presence of elevated levels of total and allergen-specific IgE in the serum of patient, leading to positive skin-prick tests to common allergens.
The multicenter PARSIFAL study in 2006, involving 6630 children age 5 to 13 in 5 European countries, suggested that restrictive use of antibiotics and antipyretics, are associated with a reduced risk of allergic disease in children.[7]