Anyone else find medications/alcohol have little/no effect?

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One of the reasons I rarely take medications or drink is because when I do, I cannot feel much of a difference. When I am prescribed pain medicines or muscle relaxers for a medical condition, I often find that they do little to alleviate pain, relax me, or alter my state of being in any way. I also feel this way when drinking alcoholic beverages, I may feel a little unbalanced or get a little quieter, but my state of awareness is never altered.

Medications never worked for me either

Absolutely. I find that interesting.
I was going to post the same question.

It applies to all mind-altering things for me. And as far as alcohol goes, I've always been the one up late at night twiddling my thumbs when everyone is well-waisted and sleeping when I've drank the same amount as them.

Hopefully I can get this to make sense:
I've also noticed that the amount of alcohol it takes for an NT to become ridiculously plastered, is the amount of alcohol it takes my brain to relax and be on a typical SOBER NT level.
Maybe our minds are too complex to let things grab hold... mind over matter. Or, maybe we metabolize faster. You would THINK that with our hyper-sensitivities we would be passed out after one beer

Great minds think alike? LOL!

I have also been in a situation where others have been totally plastered (bumping off walls, passing out when they got comfortable, couldn't remember events later, etc.), and other than needing to pay a bit more attention to walking carefully (I tend to trip a lot normally), I was fine.

I think I just had an epiphany (no pun intended)! Thinking about how alcohol typically removes social inhibitions that people put into place in their own minds. However, for many Aspies, our true nature itself is socially inhibited. Therefore, since this is ingrained in our nature, rather an artificial restriction we have created, would it not stand to reason that alcohol would have little effect on the more natural aspects of our personalities? I know there would be exceptions, but it is an interesting theory, I believe...

Something I do find interesting though is if I take benadryl for my allergies, watch out world! I'll be totally relaxed, slurring, and then passed out in no time...lol!

i inherited the genes to have a very high tolerance to narcotics and most pain pills. 2 oxycodones do nothing for me, but 3 put me out. there is no middle ground, concerning analgesia. a soma-comp codeine pill worked precisely once, it put my lights out for a day. then it stopped working. 2 aleves do almost nothing for me. alcohol, OTOH, i simply cannot tolerate any more than trace amounts of such. drat. i'd be blotto all the time if i could. valium and nitrous are the only things that work for me, but those are so hard to get in america. what is strange is that my father was the exact opposite of me in every way, in that he could find solace in alcohol and imbibe gallons of the sauce and still function. pain pills also worked for him very well. why did he give me his rotten cast-off genes?

I tend to be a happy drunk and it will lower my inhibitions to an extent. Perhaps not to the extent of an NT, but still. But I have to drink ALOT and get really drunk for that. If I'm just buzzed, the only real effect is I laugh at more stuff.

Pain meds have generally worked for me but I've only twice been on something stronger than Ibuprofen 800mg. I was on Tylenol 3 both when I had my wisdom teeth removed and when I tore all the soft tissue in my hand after ending up on the hood of a car. Oddly enough I was drunk that night. It was one of only two times I ever blacked out from booze.

They can have an effect on me, I just need more than the average person. I just have a higher tolerance.

Medications? So far, just "meh..."
Mixed results; usually unimpressive, never dramatic. (except the intense dreams from some of them )

Weed was good for a while but I tended to over-indulge and got hyper, so that had to stop.
One glass of wine is enough, and calms me like nothing else. I worry much less about what's going on around me - unless the others start getting loud and just plain embarrassing.
Hate being drunk, though, and manage to avoid that, but the light buzz is quite nice.

2 or 3 drinks in I can get a buzz. Depends on the strength of the alcohol.

I'm super sensitive to medications. I'm prone to picking up severe side effects too.

I'm weird with stimulants. Had a beer and a tea and felt drunk.

Weed does nothing for me except make me paranoid the next day.

Likewise. I'd elaborate, but I've done so around these parts twice before, and I fear becoming redundant. >_>

Yes, I've never gotten "wasted" in the sense that I go crazy/blackout. Alcohol does make me sleepy, tipsy, and sometimes nauseous if I have too much.

Pain medications, I haven't had any unusual effects.

I used to have opposite effects with coffee and tea. It made me sleepy. But now I find that if I drink coffee too late in the day, I have insomnia for the night.

Medication usually has very little effect on me. Pain killers never work for me at all. Muscle relaxers and medication that is supposed to reduce swelling and such doesn't work on me either. Most medication has little or no noticeable effect on me, or takes unusually long to start working on me.

I rarely see any point in using medication unless strictly necessary and even then I tend to forget to take it, either because I notice no difference anyway or because it's hard to add it to my routine, because by the time it has become a part of my routine I'm supposed to stop taking it, or take it differently or something.

I've never drunk alcohol, so I have no idea how much effect that would have on me.

Interesting. In medicaments I have not experienced "lack of effectiviy", but in the case of alcoholic drinks, yes, and for that "annomaly" I don't like and enjoy drinking them.

I have drunk a few times (a good number of cups) and I never felt the "symptons" that most of the people says to experience: increment of happiness, poor vision, etc, and for them they drink alcoholic drinks (because they don't have an extraordinary flavor).

It's very strange, because I'm a person who enjoys more a Coca Cola than a beer, but I don't care XD.

When they were trying to get my blood pressure under control the doctor was trying all types of drug combinations. They were in fear I was going to be one of those rare cases that could get their blood pressure to go down with medicine. Novacane also does not work well with me.