I don't think so. Yes someone may accuse you, and continue accusing you when you get upset, but they are just playing along to get to the truth.
Nothing is more important to a falsely accused than saying "I didn't do it" over and over and they are often upset in the process.
People that say things such as "everyone knows I couldn't do this!" or "ask so and so they know me!" or "I didn't do it, he did!" or "I have no idea what you are talking about" they are lying. The police are trained to recognize this.
More signs of lying:
Looking down and to the side when making a false statement.
Looking up at the ceiling while recalling events (stall tactic while their brains are trying to invent a plausible explanation)
Brushing the face with both hands (same as above)
Shaky legs
Hands crossed over the chest (tense body language)
Those are just a few. There's lots more.

I have said "I don't know what you are talking about" and wasn't lying. People have accused me of things before and I get all confused and then upset when they won't tell me what they are talking about.
So everything you said, I disagree it always means someone is lying.
Someone could be shaking because they are scared and scared they are going to get falsely accused and charged for a crime they didn't commit.