Unusual reaction to caffeine/nicotine?

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I don't react to caffeine at all. Cola or coffee have never made me feel more awake or energetic. Even the strongest energy drinks don't do anything for me.

On the contrary, cigarettes affect me very strongly. I've only smoked two in my life, for trying. It was in school, and when I was home (about 1 hour later) I suddenly felt extremely tired for no apparent reason. I had to lie down and slept for 3 hours straight.

Do you have any unusual reactions like that? I read it might be because AS affects the way the brain works...

Caffeine works only slightly with me. I've never tried cigarettes.

I have had paradoxical reactions to morphine and adrenaline:
Morphine - after surgery I was given morphine. As is common knowledge, morphine has the side-effect of calming the person down and making them sleepy. I was awake for three days straight on a constant high.
Adrenaline - injected local anaesthetics are commonly mixed with a small dose of adrenaline to prevent the local anaesthetic from spreading. I am fine with needles, but after receiving the local anaesthetic, I collapsed and had a blood pressure of 60 over 30. Adrenaline is supposed to increase blood pressure!

sigerates don't have the same effect on me then on other people or i just don't like the effect.

Caffeine and chocolate give me migraines that last for days on end and include numbness, inability to speak and auras. I've never smoked, so I wouldn't know about the nicotine part. Cigarette smoke only aggravates my respiratory issues.

I have a fast metabolism and overall sturdy chemical systems, so i tend to have a delayed and/or weak reaction to most chemicals. Everything seems to affect me in the normal way. It just has to really work to do it. It's a double edged sword, really. I have a high alcohol tolerance and rarely have hangovers, but two hits of Novocaine straight to the gums still lets me feel dentistry pain. =/

caffeine has no effect until I've had too much, then I'm jittery. Quite certain this is a result of complete and total addiction to the substance, 2 pots a day ya know.

Cigarettes. I smoked for a year and became totally addicted after one cigarette. The effect and feeling was great and really obvious to me and one or two were enough for a whole day for me so I did not smoke a lot during that year. I quit 12 years ago and even after watching my mom die from lung cancer I STILL get nic fits and want to smoke. I never give in though.

Benedryl makes me jittery, not drowsy.

My spinal wore off during my c-section. But other anaesthetics last longer than they should.

I usually do not react at all when I consume caffeine. However, there is one exception. I don't know exactly what the put into this energy(Chinese medicine plus caffeine and passionfruit?) but whatever it was it made me go ape s**t. Literally, I was jumping up and down for at least forty minutes. I had palpitations. My autistic brain threatened to explode...I'll probably not buy this again.

Caffeine affects me quite badly, I become manic and jittery. For this reason I know longer drink coffee, tea or Cola. I smoked for about a year when I was 12 and I didn't notice any particular reaction. Alcohol affects me also, I stay drunk for a very long time and then feel very depressed, which is why I don't drink either. Painkillers work well on me but send me to sleep, after prescription painkillers I can sleep for 12 hours quite easily. I don't drink anything I wouldn't give to a 5 year old and that seems to work for me.

Caffeine in moderate to high doses doesn't seem to affect me at all. I can switch from decaffeinated to ordinary tea and coffee and I don't feel any different. I used to think caffeine made my eyelid twitch but it doesn't. But, if I take a large dose of caffeine (like lots of Pro-Plus tablets), my heart might start racing.

Nicotine makes me feel nausea if I eat too much nicotine gum. But apart from a slightly weird feeling in my forearms on withdrawal, I don't seem able to get addicted to it. I can get very attached to a smoking or gum habit, but it seems to be all about the rutuals........take only the nicotine out of the equation and I don't really notice.

I can't endure most of the sensory stimuli that result from smoking tobacco. I don't have a clue how I react to nicotine because I can't possibly get it into my system xd

I am very sensitive to all kinds of substances, caffeine and nicotine included. I've smoked a few times in my life and I didn't like it that much, I just got buzzed and dizzy, nothing interesting, nothing very pleasurable. I also took once a hit of nicotine from an e-cig and got lightheaded and feeling funny for hours. Nicotine affects me more than other people, but it's not an interesting sensation for me. I'm fine with tobacco in joints, but I guess it's because the weed high mitigates the effects of nicotine. However, one day, when I was high on opiates, I took a cab and just inhaling the second-hand smoke coming from the driver made me melt with pleasure in the backseat. Apparently, there are some interactions between opiates and nicotine (I know of many people who have taken up smoking after getting into heroin).

Caffeine affects me very strongly, but it never gets me jittery. If I ingest large amounts from various sources (coffee, teas, pills) in a short amount of time, it gets me quite high. But I don't get all hyped up - I get mellow and sleepy, almost stoned instead. Might be because of my ADHD...

I get easily drunk from low amounts of alcohol. I also get very high from minute amounts of opiates - I'm not even abusing them, I'm just taking my prescribed dose and it's enough to get me high (I am instructed to take 15-30 mg of codeine; when I take 15, I'm still sober, but 30 mg rock my world when my tolerance is low). I only need a few hits of weed to get stoned, while my friends smoke far more and don't get as high as I do. I get extremely sedated from non-sedating antihistamines. And so on... I don't know why though... I haven't done any other drugs, so I don't know if stronger ones effect me just as much.

And I'm also one of the very few people in the world that had an oculogyiric crisis (eyes uncontrollably rolling in different directions - a type of tardive dyskinesia) after 6 doses of metoclopramide (Reglan), that was prescribed by my GP.

So, yes, as far as being sensitive goes, I certainly am sensitive to psychoactive drugs and to all kinds of other chemicals...

_________________
Probably 75% Aspie, 25% NT... and 100% ADHD

Aspie-quiz results:
Aspie score: 138 of 200 / NT score: 78 of 200 => Very likely an Aspie.

Caffeine doesn't have the desired effect on me. I just get anxious and I can feel my heart pounding and it certainly doesn't make me any more alert. I used to smoke 30 a day many years ago so you could say that nicotine works.

Used to smoke, the cigs acted like a pacifier for me, the nicotine was a bit of a sedative.
Caffeine calms me. I make my coffee really strong, and the first 1 or 2 cups sooth me very well.
Alcohol puts me to sleep. Okay, I don't drink much, maybe 2 beers a week.

I don't smoke, due to a bad experience with smoking (which was only once), so I wouldn't know how it affects me apart from the smoke making me choke. I'm fine with other people smoking around me.

Caffeine has a varying effect. When I first started drinking coffee, I felt this energy surging through my body. But when I continuely drank it, I don't feel energetic as much as usual; I do wake up after only a few hours of sleep if I drank coffee right before going to bed (which is a bad habit of mine).
I had one energy drink a long time ago, and I felt pretty 'high' for several hours.

I've had a strange occurrence with morphine once. This was at the age of 3, when my mother took me to a doctor for tests, in order to find a possible cause for my Autism. When they tried to take a sample of my Cerebrospinal fluid from my spinal cord, I was too hyper to be still, so they had to inject morphine into me so they could safely take that sample.
Now this is where it's getting weird. The doctor told my waiting mother that I would sleep at least a couple of hours. But I woke up after only a short while in the middle of the morphine's effect, and I couldn't move a muscle in my body, except my face.

So I've no idea if it could had been because I was hyperactive, or if there was some other reason.

caffeine doesnt really make me alert
I can still fall asleep after chugging a bottle of energy drink