for me the first line of defense is my ADLs. So whether i feel like it or not i get out of bed, do the dishes, take a shower, eat something nutritious, get out of the house if even for a short while (20 minutes of sunlight has been shown to be anti-depressive), do something i enjoy, do something for someone else.
it's generally a good idea for me to have a counselor i like that i see regularly, and seeing and talking with a good therapist is my 2nd line of defense.
cognitive behavioral therapy has never worked for me. it has to be relational/gestaltish. usually my depression is related to fear or anger i'm out of touch with. once i can feel and deal with the feelings, including making life changes, my depression usually improves.
sometimes though under great loss or great stressors my depression will be simply whatever you call it, unresponsive and becomes particularly deep and scary, i go to an antidepressant. the only one that works for me is wellbutrin (buproprion). SSRI's do nothing for me at all. Wellbutrin is an SNRI. It has the added benefit of drastically reducing my urge to smoke and dampening my appetite, both of which tend to get stronger when i'm down.
hope some part of that helps.
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161 Aspie / 51 NT - Aspie Quiz (very likely an aspie)
36 - AS Quotient
115 aloof, 123 rigid, 89 prag - Aut/BAP
24 - HSP / ADD Quiz- 41, Inattention: 24, Hyperactive/Impulsive: 17
"Odd and different is beautiful" -- Tyra Banks