I smoked a few acre's worth when I was in my 20s, then I got married, had a family and couldn't afford to waste money on weed, so I gave it up. I never felt 'dependent' on it, I just enjoyed it and it helped me socialize more comfortably. It was one of those things I did when it was available, and did without when it wasn't. These days, I no longer have the connections to even acquire it and thanks to Dubya, if you get busted for any drug offense whatsoever, you lose your SS Disability forever.
During that period of my life, I also had access to many other recreational chemicals, but most I chose to leave alone. For instance, I never got what cokeheads saw in blow that was worth spending such outrageous amounts of money on. It had very little effect on me, other than making me rather tense and jittery, like too much coffee, and that's quite unpleasant. Fortunately, I saw a written recipe for meth and wouldn't touch that rat poison with a ten foot pole.
Current research is showing Psilocybin, the active ingredient in magic mushrooms to be an excellent and effective antidepressant and that certainly reflects my personal experience. Alas, that, too was ages ago.
OTOH, I do have the bad habit of using alcohol as a sleep aid. I just don't trust laboratory pharmaceuticals with all their side effects. However, that's the only time I drink, right before bedtime. Never during the day, even on barbecue holidays, when it's acceptable.