I wouldn't find that offensive.
As long as you don't insult somebody with Locked-in Syndrome, I don't see how offensive it can be to such a person. I wouldn't be 100 percent positive--unless somebody with LIS actually states that he/she is not offended by it.
WP has the potential to be a salvation/revelation for people with Locked-In Syndrome.
I wonder if there's ever been anybody on WP who has that condition.
Maybe if you write about it, it might inspire someone with LIS to post.
To me, it would be fascinating to read the thoughts of such a person.