Hypermobility and ADHD/ASD

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Joint Hypermobility and Its Neurological Implications

‍Joint hypermobility, particularly prevalent in conditions like Ehlers-Danlos Syndrome (hEDS), is more than just a physical attribute; it has notable neurological implications. Recent studies have discovered that individuals with joint hypermobility, including those with hEDS, often exhibit unique brain functions, especially in regions like the amygdala that are involved in processing emotions and fear. This discovery suggests a complex interplay between physical and neurological traits in these individuals.

The Overlap of Ehlers-Danlos Syndrome with ADHD and Autism

‍A growing body of evidence indicates a significant overlap between Ehlers-Danlos Syndrome and neurodevelopmental disorders such as ADHD and autism spectrum disorder (ASD). A Swedish national registry study and other research have shown a positive association between EDS and these neurodevelopmental disorders, suggesting a shared underlying pathophysiology​​. Notably, ADHD is more common in individuals with hEDS compared to those with HSD, with prevalence rates as high as 46% in certain age groups​​.