Proof! "Risperidone No Better Than Placebo"

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Zarathustra
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05 Jan 2008, 11:50 am

Well folks, it's gold plated and from the UK's leading medical journal www.thelancet.com/journals/lancet/artic ... 0/abstract


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ouinon
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05 Jan 2008, 11:58 am

What a surprise! :lol: :lol: :lol:

8)



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05 Jan 2008, 12:04 pm

Good gracious. I knew someone who took that stuff - it basically turned him into a morbidly obese zombie. Such a pity. That stuff is LETHAL and whoever deals in it need to be brought to trial pronto charged with crimes against humanity!


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zendell
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05 Jan 2008, 12:31 pm

Unfortunately, doctors will probably still prescribe it. I knew people who were on these drugs. It doesn't treat autism. It zaps the energy of autistics (which reduces some autistic behaviors) to make it more bearable for people who are forced to take care of them. For example, autistics might get angry and violent when they are misunderstood. Instead of making an effect to understand, unloving caretakers will drug them to suppress their violence. Even though they will still be angry that no one cares or tries to understand them, they won't have enough energy to do anything about it. I think it is horrible to reduce autistic behaviors with psychiatric drugs. These drugs should NEVER be used on people with autism or AS. There's also studies showing psychiatric drugs cause permanent brain damage.



jjstar
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05 Jan 2008, 12:44 pm

zendell wrote:
Unfortunately, doctors will probably still prescribe it. I knew people who were on these drugs. It doesn't treat autism. It zaps the energy of autistics (which reduces some autistic behaviors) to make it more bearable for people who are forced to take care of them. For example, autistics might get angry and violent when they are misunderstood. Instead of making an effect to understand, unloving caretakers will drug them to suppress their violence. Even though they will still be angry that no one cares or tries to understand them, they won't have enough energy to do anything about it. I think it is horrible to reduce autistic behaviors with psychiatric drugs. These drugs should NEVER be used on people with autism or AS. There's also studies showing psychiatric drugs cause permanent brain damage.


Well said


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zendell
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05 Jan 2008, 12:49 pm

Results of study:

Quote:
Aggression decreased substantially with all three treatments by 4 weeks, with the placebo group showing the greatest change


It seems the people taking care of them treated them better when they were on the drugs. Aggression was reduced by 79% with placebo compared to 58-65% with the drugs. They probably treated them more like humans after they thought the drugs made them more normal. When they were off drugs, they probably treated them like inferior sub-humans and treated them accordingly which made them more aggressive. Their caretakers need to adjust their attitude.

It looks like this was an independent study. Not surprisingly, studies by the drug company who manufactures Risperdal found if effective and the FDA approved it for treating autism. Drug company studies (which make up the majority of research) almost always find their drugs effective. Independent research often conflicts with drug company research.



logitechdog
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05 Jan 2008, 12:52 pm

... Error



Last edited by logitechdog on 05 Jan 2008, 1:07 pm, edited 1 time in total.

zendell
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05 Jan 2008, 1:04 pm

ok



Last edited by zendell on 05 Jan 2008, 1:43 pm, edited 2 times in total.

KingdomOfRats
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05 Jan 2008, 1:07 pm

Am have read about this on BBCs' health section before [on BBCs' digital itext],but they said it was research on people with learning disabilities,not intelectual disability.
Are the lancet classing them both as the same thing?
Anyway,in this day and age with so many alternative lesser risk medications available,why still go for risperdal?


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logitechdog
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05 Jan 2008, 1:07 pm

No just made a mistake of opening loads of threads at once & ended up posting everything in the wrong place lol so just ignore it lol



Zarathustra
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05 Jan 2008, 1:23 pm

Zendal, nice explanation of placebo effect in this study. I was wondering what was going on...


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KimJ
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05 Jan 2008, 1:34 pm

Disclaimer, I don't give drugs to my son or take them myself. So, I'm generally biased against antipsychotics-even in so-called desperate situations.
That said, this study isn't "proof" of anything. It's a good insight into the use of such medications and how treatment corresponds with medicating people. However, like has been mentioned, the subjects were treated differently and that may have had a profound effect on the medications (including the placebos). Especially if the staff was unaware of who was getting what (like a double-blind study). Also, this study wasn't performed with strictly autistic people but varying "disabilities". So we don't really know why the results were so unexpected. Who was helped? Who wasn't?

I really think this study opens up a new discussion. It certainly doesn't close the old one.



Zarathustra
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05 Jan 2008, 3:36 pm

My analysis didn't go beyond noticing that the placebo had a greater effect than two not very nice, major tranquillizers...


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KimJ
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05 Jan 2008, 4:40 pm

Your "analysis" claimed the study was "proof", which it is not.



Zarathustra
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05 Jan 2008, 5:46 pm

Don't really understand why?


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