Firstly I have to say that I am not sure that I have AS. But if so, there seems to be a genetic component - my cousin is diagnosed and she suspects one of her niece and nephew of having it also.
On the other hand, neither of my sisters or my parents show obvious signs of being AS (perhaps the odd trait). My mother (who doesnt think I have AS, but doesnt really know much about it) thinks I am different because of a drug that she took whilst pregnant - unfortunately she cant remember the name of it, but she didnt take it with my sisters. Several of her friends also took it and the resulting children were also a bit different from normal.
Overall, I think that autism is genetic in basis, but that environmental factors are likely to have a strong influence on whether the genetic predisposition is expressed or not. I wouldnt be surprised if there are in fact many types of autism (not just an AS/Kanner's division, but many other subgroups), which vary in the groups of genes affected and the environmental components.
There are several significant AS traits that I am lacking, yet there are others in which I am very defective, and yet other traits I have which are not on any clinical AS scale, but are not normal. Sometimes I wonder whether I have a different varient of autism which is not yet described (or perhaps something else entirely different).
Also, the genetic component in my family seems to affect females more than males, which is the opposite of usual autism cases. As a scientist I would like to do some sort of study to find out the genetic basis and environmental influences of autism, but unfortunately I specialised in the wrong area of biology.