"I can't be bothered"
"Wait""Not now ... maybe later"
"I'm too upset right now"
"I've too much going on right now"
"I've bigger things to deal with right now"
"No""Go away"
"Stop bothering me"
"It's not my job"
"Take your trivial matters elsewhere"
I guess you'll just have to consider the context to determine the specifics, but mostly it means:
"I'm not currently interested in what you have to say; and while I'm not making any promises, you can try me again later if need be."
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The mere fact that science may not yet adequately explain an object, event, or experience does not mean the immediate explanation should automatically default to a conspiratorial, extraterrestrial, paranormal, or supernatural cause.