Depends on the context for me.
I don't mind people saying AS symptoms are stupid in the sense of 'useless', perhaps 'painful to have' or just 'annoying' 'hard to life with' 'insensible' 'impossible to understand' and so on. I might say that myself.
I very much mind it if they say stupid and mean to say the symptoms are not real, are silly, not truly a problem, that you could stop having these, that they make you less of a human, that they're a flaw, mean you're defective, ugly, disgusting, that they make you an idiot and so on.
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Autism + ADHD
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The trouble with having an open mind, of course, is that people will insist on coming along and trying to put things in it. Terry Pratchett