Take any role, be it tv, film, game, theatre, job role etc..., and recommend a celebrity or other known character to fill that role. The only rule is that the chosen character must not already fill that role. As in Batman cannot be Batman, Tobey Maquire cannot be Spiderman etc. The game is not serious, so feel free to be as amusing as possible. I'll start with a few:
Britney Spears as Borg Queen (Star Trek)
Yoshimitsu (Tekken) as Talk show host
Homer Simpson as Agent Smith (The Matrix)