Study finds an increased disease burden in middle-aged and older autistic adults
Quote:
Older autistic adults have a significantly higher risk of injury, especially self-inflicted, and physical conditions such as type 2 diabetes, anemia, heart failure and COPD. This is according to a large-scale registry study from Karolinska Institutet in Sweden published in The Lancet Healthy Longevity.
In the population-based study, the KI researchers linked different national registers and compared the risk for five types of injury and 39 age-related physical conditions in people over the age of 45. Of the four million-plus people born between 1932 and 1967, 1,930 women and 3,361 men had an autism diagnosis. For each physical condition, they evaluated the 25-year cumulative incidence and the relative risk in autistic people compared with non-autistic people of the same sex and age.
Seven-fold risk of self-harm
Autistic people had a higher risk of four of five studied injures, for which self-harm accounted for the greatest risk increase, followed by poisoning, falls and other physical injuries.
The risk of self-harm was worryingly high, a full seven times higher than in non-autistic people," says Liu. "Reasons behind this remain largely unknown. One possible contributing factor could be mental health conditions that commonly co-occur with autism, such as anxiety and depression."
The researchers also found a risk increase for 15 physical conditions. For example, autistic people had three times the risk of anaemia and glucose dysregulation and almost double the risk of heart failure, type 2 diabetes, and COPD (chronic obstructive pulmonary disease).
Multiple contributory factors
Since this was an observational study, no causal relationships can be ascertained, and the researchers were not able to take into account variables such as socioeconomic status. Furthermore, given that the study used Swedish registers, it is difficult to make generalisations to other countries.
The study was financed by the Swedish Research Council and Servicer Affaires Medicales. Co-author Henrik Larsson has received speaker fees from Evolian Pharma and Shire, and research grants from Shire (unrelated to this present study).
Take care folks, don’t forget your yearly physical, etc.
_________________
Professionally Identified and joined WP August 26, 2013
DSM 5: Autism Spectrum Disorder, DSM IV: Aspergers Moderate Severity.
“My autism is not a superpower. It also isn’t some kind of god-forsaken, endless fountain of suffering inflicted on my family. It’s just part of who I am as a person”. - Sara Luterman