And from a book I recently read of one mother's account of working and fighting to get the right care for her son with OCD.
Quote:
Saving Sammy: Curing the Boy Who Caught OCD, Beth Alison Maloney, 2009.
Page 35:
I was at my desk the following day when I heard loud pounding coming from the second floor. I ran downstairs and screamed. Sammy was banging his head against the sliding glass door.
"Sammy! Stop! Stop!" I yelled.
"I can't!" he sobbed. "It's like a mental itch!"
Quote:
Pages 221-22:
Augmentin is an extremely powerful antibiotic that is often prescribed when penicillin is not effective. It is largely composed of penicillin, but it also contains something called clavulanic acid. Clavulanic acid prevents the breakdown of penicillin,; it makes the penicillin more effective. I often wondered why Augmentin had worked for Sammy when so many other powerful antibiotics had failed him.
I started thinking about inflammation in Sammy's brain after I read an article in the New York Times about Alzheimer's and Augmentin. It reported that when a group of Alzheimer's patients were given daily doses of Augmentin, their memories improved. The article quoted experts who theorized the possibility of inflammation in the patients' brains. I also had anecdotal information about elderly patients who made remarkable recoveries when fluid was released from their brains. Perhaps fluid on the brain creates a pressure similar to swelling. The body swelled when it was pounded; why not the brain when assaulted by antibodies? Could this be the "mental itch" that had caused Sammy to bang his head when he first got sick?
Dr. Nicolaides believes there is something to the anti-inflammatory premise. One of her PANDAS patients, who also suffered from asthma, had his OCD symptoms abate when he took prednisone for the asthma. Prednisone is a steroid that is also an anti-inflammatory. As the prednisone was withdrawn, the OCD symptoms returned. This led her to believe that there was inflammation in the basal ganglia. She wondered if perhaps swelling is caused when the antibodies and antigens react.
Okay, so a couple of single patient reports, which are also called anecdotal reports. Plus, the one study in the
New York Times about Alzheimer's. But it is intriguing. I think it's worth exploring further.