Alcor Life Extension Foundation - Cryonics
02 Mar 2012, 7:30 pm
conan wrote:
it's not that simple. if you looked at the actual papers the scientist were writing they would really not be jumping to conclusions like almost every news source about science does.
it is fascinating stuff and will play a part but like i said. it is a small part of the picture. You can't cure aging or cancer with one enzyme. one problem is that there will be other problems that arrise if you then decide to extend the cell's proliferating capacity beyond normal.
Why is it that cancer cells are able to proliferate indefinitely rather than 80 times? partly because of telomerase in some cases! have a look at the HeLa cell line. from wiki "A proposed treatment for cancer is a telomerase inhibitor that would prevent the restoration of the telomere, allowing the cell to die like other body cells." This and many other things should lead one to the conclussion that gene expression leading to protein synthesis and it's effect are entirely contextual.
i'm not saying it's not going to happen but i'm saying just inducing expression of one gene does not mean much, particularly in multicellular organisms. it's certainly will happen if research is pushed in the right direction.
i'm not sure about stem cells and the Hayflick limit. here says that " Stem cells, by definition, have not yet been fully differentiated, and therefore many of these cells may continue to regenerate new cells for the entire lifespan of the organism, without limit, thus constituting a notable exception to the Hayflick limit in humans and other organisms."
i think there are many many exceptions to the hayflick limit
i can't say i'm that familiar with cancer or the process of aging beyond cell senescence and apoptosis and a bit about the cell cycle but i do know that any given cell is full of interdependencies, trade offs, contexts etc etc. still, it is an interesting point and i hope you become a biologist!
it is fascinating stuff and will play a part but like i said. it is a small part of the picture. You can't cure aging or cancer with one enzyme. one problem is that there will be other problems that arrise if you then decide to extend the cell's proliferating capacity beyond normal.
Why is it that cancer cells are able to proliferate indefinitely rather than 80 times? partly because of telomerase in some cases! have a look at the HeLa cell line. from wiki "A proposed treatment for cancer is a telomerase inhibitor that would prevent the restoration of the telomere, allowing the cell to die like other body cells." This and many other things should lead one to the conclussion that gene expression leading to protein synthesis and it's effect are entirely contextual.
i'm not saying it's not going to happen but i'm saying just inducing expression of one gene does not mean much, particularly in multicellular organisms. it's certainly will happen if research is pushed in the right direction.
i'm not sure about stem cells and the Hayflick limit. here says that " Stem cells, by definition, have not yet been fully differentiated, and therefore many of these cells may continue to regenerate new cells for the entire lifespan of the organism, without limit, thus constituting a notable exception to the Hayflick limit in humans and other organisms."
i think there are many many exceptions to the hayflick limit
i can't say i'm that familiar with cancer or the process of aging beyond cell senescence and apoptosis and a bit about the cell cycle but i do know that any given cell is full of interdependencies, trade offs, contexts etc etc. still, it is an interesting point and i hope you become a biologist!
i see your point, scientists have said that Telomerase is always present in cancer but to be fair they are working on having Telomerase create mutated Telomeres in cancerous tissue
http://mcr.aacrjournals.org/content/3/9/477.full
studies in mice show it greatly decreased tumor growth and some regression of the tumors
that's what i love about science, is its flexibility
i have a couple PDF docs on the subject, since i don't have a computer anymore, i am on my PS3 so here are the links to a few of them
http://staff.washington.edu/mwhiddon/Shayetal.pdf
http://www.agnos.nl/downloads-2/files/B ... ls2007.pdf
http://www.terraternal.com/Files/Telome ... dAging.pdf
http://www.benthamscience.com/open/tols ... 3TOLSJ.pdf
last year i wrote my own little thesis on Life Extension using synthetic biology and stem cells for my AP English class, me and several teachers got together to review it and biggest problem was cancer. i noticed cancer is the biggest problem of every theory for Life Extension
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Last edited by TheKing on 02 Mar 2012, 7:41 pm, edited 1 time in total.
02 Mar 2012, 7:37 pm
conan wrote:
it's not that simple. if you looked at the actual papers the scientist were writing they would really not be jumping to conclusions like almost every news source about science does.
it is fascinating stuff and will play a part but like i said. it is a small part of the picture. You can't cure aging or cancer with one enzyme. one problem is that there will be other problems that arrise if you then decide to extend the cell's proliferating capacity beyond normal.
Why is it that cancer cells are able to proliferate indefinitely rather than 80 times? partly because of telomerase in some cases! have a look at the HeLa cell line. from wiki "A proposed treatment for cancer is a telomerase inhibitor that would prevent the restoration of the telomere, allowing the cell to die like other body cells." This and many other things should lead one to the conclussion that gene expression leading to protein synthesis and it's effect are entirely contextual.
i'm not saying it's not going to happen but i'm saying just inducing expression of one gene does not mean much, particularly in multicellular organisms. it's certainly will happen if research is pushed in the right direction.
i'm not sure about stem cells and the Hayflick limit. here says that " Stem cells, by definition, have not yet been fully differentiated, and therefore many of these cells may continue to regenerate new cells for the entire lifespan of the organism, without limit, thus constituting a notable exception to the Hayflick limit in humans and other organisms."
i think there are many many exceptions to the hayflick limit
i can't say i'm that familiar with cancer or the process of aging beyond cell senescence and apoptosis and a bit about the cell cycle but i do know that any given cell is full of interdependencies, trade offs, contexts etc etc. still, it is an interesting point and i hope you become a biologist!
it is fascinating stuff and will play a part but like i said. it is a small part of the picture. You can't cure aging or cancer with one enzyme. one problem is that there will be other problems that arrise if you then decide to extend the cell's proliferating capacity beyond normal.
Why is it that cancer cells are able to proliferate indefinitely rather than 80 times? partly because of telomerase in some cases! have a look at the HeLa cell line. from wiki "A proposed treatment for cancer is a telomerase inhibitor that would prevent the restoration of the telomere, allowing the cell to die like other body cells." This and many other things should lead one to the conclussion that gene expression leading to protein synthesis and it's effect are entirely contextual.
i'm not saying it's not going to happen but i'm saying just inducing expression of one gene does not mean much, particularly in multicellular organisms. it's certainly will happen if research is pushed in the right direction.
i'm not sure about stem cells and the Hayflick limit. here says that " Stem cells, by definition, have not yet been fully differentiated, and therefore many of these cells may continue to regenerate new cells for the entire lifespan of the organism, without limit, thus constituting a notable exception to the Hayflick limit in humans and other organisms."
i think there are many many exceptions to the hayflick limit
i can't say i'm that familiar with cancer or the process of aging beyond cell senescence and apoptosis and a bit about the cell cycle but i do know that any given cell is full of interdependencies, trade offs, contexts etc etc. still, it is an interesting point and i hope you become a biologist!
i used to want to be a BioMedical Gerontologist but im deciding to be a US History and Gov/Econ teacher, my aspie obsession is with learning and that led me to the Life Extension movement, i figure the longer i live the more i can learn. the Life Extension movement led me to Transhumanism and the exciting frontier of the future
_________________
WP Strident Atheist
If you believe in the Flying Spaghetti Monster, have accepted him as your lord and savior, and are 100% proud of it, put this in your sig.
