I have pretty slow internet, so I can usually read the entire profile before the picture(s) even loads. Sometimes, it only takes reading one or two lines of a profile before I hit the "skip" button, and thus never even see the picture.
But, I confess, there has been a time or two when I read the profile, thought to myself "hmmn, kind of interesting" and then saw the picture and said "OH HELL NO!" The biggest reason for this is that men (at least in my age group) will often describe themselves and "handsome and fit" and then their photo shows that they weigh at least 300 lbs and strongly resemble the north end of a southbound mule.
I certainly don't require that a man be classically handsome (I tend to be attracted to facial expressions, not features), but if the guy doesn't have a sufficient level of self-awareness (or at least a little humility) to describe himself somewhat honestly and accurately, then I'm not interested.