Yes, I've been going through the same thing for a year, ever since I was diagnosed. It's finally starting to get better, because I now realize that I'm always going to struggle with reading social cues, and my Theory of Mind still stinks - I can't easily put myself in other's shoes without working really hard at thinking about it. Like you said, this is sooo much work that it just becomes frustrating to deal with people at all. I used to be so happy and carefree when interacting with people, and now I realize that I used to unintentionally hurt their feelings a lot. Ironically, now that I'm less interested in interacting with people or trying to connect with them, they actually seem to like me better!! How twisted is that? I guess it's because I'm not as pushy and talkative now, because I no longer put forth as much of an effort to share my opinions or feelings with other people. Now that I often act more reserved (in a way that I would have used to call "snotty"), NTs actually respond better to me. What a joke! But I'm getting used to it. And my self-esteem is improving, so hang in there - yours will too! Don't concentrate on reading too much into other's reactions. Just concentrate on communicating with others in a style that you yourself would like if you were in the other person's shoes. And then if it works, fine. If it doesn't, fine. Either way, you'll be able to feel good about yourself and know that you did your best to connect with the person, and you can leave it at that without beating yourself up. It takes awhile to get to this point of self-acceptance, but you'll make it. Just have patience with yourself!!