Miyah, I have one of those "friends" too....
No matter how you try and rationalise it, they are a pain. Are you close enough to say (jokingly) "yeah, enough of the bragging now, or I'm going to get annoyed"? Or maybe she feels a bit inadequate, or maybe she is just not all that nice, or maybe no-one but you will listen to her brag
Sadly, I can't do that with the person I know- her facebook status is always about what research papers she's published in, how she's getting loads of funding for her work....and all I can think is, "but her boyfriend's a cokehead and she doesn't know"......
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Other people are people too.