Hmmn, used to use it WAY too much..
Nowdays I'd use it probably once a week, but never really more than that, and it has no adverse effect on me at this rate... Just helps me do the once a week socialising that I've decided I'll enjoy..
It greatly affects the way music hits me, usually I hear the parts of the sound and with a choice put them together, when I'm stoned the whole washes over me in a different way..
So.. be careful with it, try it if you want, but don't make it a way of living!
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All hail the new flesh, cause it suits me fine!