Short review of "Lessons learned from studying syndromic autism spectrum disorders" (see link for articles' pdf).
An interesting summary of present knowledge about the neurobiology of the four most common monogenic syndromic ASDs.
I personally don't agree with the widely accepted postulates accompanying the direction of research this article represent because I think it's a misconception to classify non-syndromic ASD as a disease, worse even: one which should be cured.
Nonetheless, the data researched for this article has been collected and presented for the first time in a very concise and elegant way, like never before, and I must add it is fairly understandable even for non-scholars like me.
I really hope they will be able to develop therapies to treat syndromic ASDs, I however have completely different opinions as to what to conclude based on all the presented data: I think it perfectly illustrates the gap between pathology-based autistic traits and hereditary expressions of neurodiversity. The former are monogenic, the latter not. Why then consider them as a whole? Anyway there are many other conditions which produce autistic traits (Acquired brain injuries, for example). You can keep trying to push a square into a round hole, or you can spare time and money for where it really matters: Rett, Angelman, fragile X syndrome, etc. Don't you think?
https://pdfs.semanticscholar.org/21b0/3 ... b92f8d.pdf
Last edited by Kamil Fuchs on 24 Mar 2017, 4:06 am, edited 1 time in total.
24 Mar 2017, 3:59 am
