I don't mind parts of being female, but the societal expectations are probably the most annoying part of being a female. You're supposed to look like a stick with big boobs, have all of your hair perfectly groomed, clear skin, tanned, wear a lot of makeup "naturally" so you don't look like a slut, love all gossip, get all goo-goo gaga about babies and adorable animals, PMS being the only reason you're upset, always on a diet, loves shopping sprees and shoes, obsessed with Twilight and the like, giving empathy to everybody, always playing mind games, bad at math/science, love reality shows, hate sports and getting dirty, being obsessed with marrying and weddings, etc. I could go on for a long time on this list.
But the worst part is the double standards. It's acceptable for a man in my area to be overweight/obese and have ridiculous appearance standards for who they will date, but no woman is ever supposed to impose even weight standards on their boyfriends. And if a woman gets to 30 and isn't married she's desperate and everyone is pressuring her to marry the next man who walks by her because she's old, while men who are single and 30 are just enjoying the single life and can always find some 20 year old who will date them.
I don't mind physically or mentally being female, it's just the assumptions of society that make life more frustrating than anything.